Detection and Analysis of Clinical Microbial Infections, Third Edition
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 873
Special Issue Editor
Interests: implant-associated infections; anti-infective substances and strategies; virulence factors; bacterial biofilm; bacterial molecular epidemiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is the third edition of our previous Special Issues, “Detection and Analysis of Clinical Microbial Infections” and “Detection and Analysis of Clinical Microbial Infections, Second Edition”.
Microbiological infections and diseases can be caused by bacteria, viruses, parasites, and fungi. This Special Issue has caused worldwide concern and requires the rapid detection and identification of the pathogens responsible for microbial infections. The first crucial and complex phase of the diagnostic process is the definition of the methods for collecting microbiological samples. In fact, depending on the heterogeneous diffusion and probable low number of pathogenic microorganisms, as well as on the chosen diagnostic method that will be used, sampling can be considered a difficult step, especially in chronic infections. The identification methods can be grouped into different clinical–diagnostic categories, namely, methods of isolation and culture with the determination of phenotypic and biochemical characteristics; morphological observation under microscope, particularly used for mixed microbial populations and non-culturable pathogens; antigenic tests, commonly used for their rapidity and simplicity; serological assays, with high specificity and sensitivity; and molecular biology techniques, for a definite microorganism recognition. "Omics" technologies, in particular genomics (PCR, PFGE, ribotyping, RFLP, RAPD-PCR, DNA sequencing, WGS) and transcriptomics (qPCR, RNA sequencing), but also proteomics (MALDI-TOF MS) and metabolomics (mass spectrometry-based methods), with an improved advancement of their limit of detection, are considered the cornerstones of clinical microbial analysis.
In addition to the demand for rapid and accurate diagnosis, due to new emerging microbial pathogens, there is a need for greater standardization of testing and centralized laboratories with the ability to collect and analyze large quantities of samples and perform various identification techniques.
Research articles and systematic reviews are both welcome.
Manuscript topics may cover the following topics:
- Identification of unculturable pathogens and mixed microbial populations.
- Sampling, culture, and isolation of the pathogen responsible for infectious diseases.
- Advantages and limits of clinical microbial identification techniques.
- New molecular biology techniques for microbial identification.
- Standardization of techniques and sample data centralization.
Dr. Stefano Ravaioli
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- microorganisms’ detection and analysis
- clinical microbiology
- identification technologies
- new identification methods
- heterogeneous dissemination
- unculturable pathogens
- mixed microbial populations
- new emerging pathogens
- genomics
- transcriptomics
- proteomics
- metabolomics
- standardization of testing
- sample data centralization
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