Ticks and Threats: Insights on Tick-Borne Diseases

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Public Health Microbiology".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 137

Special Issue Editors


E-Mail Website
Guest Editor
Animal Health Department, Experimental Zooprophylactic Institute of Southern Italy, Portici, Italy
Interests: parasites; public health; ticks; tick-borne diseases; wildlife; zoonoses

E-Mail Website
Guest Editor Assistant
Forestry and Forest Products Research Institute, Tsukuba, Japan
Interests: ecological parasitology; field parasitology; infectious disease ecology

Special Issue Information

Dear Colleagues,

As is well-known, tick-borne diseases represent a major global public health challenge due to the plethora of bacterial, viral, and parasitic infections affecting animals and humans. To date, the occurrence and emergence of tick-borne diseases has been considered across different geographical settings due to their complex epidemiology, this depending on various sociodemographic aspects. For example, agricultural strategies, deforestation, and global warming are strongly involved in altering ecosystems, affecting tick–host interaction and the circulation of tick-borne pathogens. In addition, the increased urbanization of various wildlife species in urban and suburban areas has further increased the circulation, transmission routes, and exposure risk of tick-borne zoonotic pathogens to pets, farm animals, and humans. Accordingly, this Special Issue is open to original research, review articles and case reports related to the above aspects, with the aim of contributing to the understanding of tick-borne diseases. Accordingly, this Special Issue is open to original research, review articles, and case reports addressing aspects related to tick-borne diseases and related agents in animals and humans, including the following topics:

  • The ecology and epidemiology of ticks and tick-borne infections;
  • Microbial pathogenesis of viral, bacterial and parasitic infections in the vertebrate host;
  • The role of synanthropic wildlife in the epidemiology of tick-borne pathogens;
  • Novel approaches in the monitoring and surveillance of tick-borne infections;
  • Spatio-temporal models to predict the distribution, abundance, and spread of ticks, as well as the agents transmitted, including the introduction of invasive tick species and new pathogens into previously free areas;
  • Technically sound control methods of tick populations, including symbiotic control of ticks by tick endosymbionts;
  • Recent advances in the knowledge of tick-borne infections by in vivo and in vitro experiments;
  • Frontiers in the development of anti-tick vaccines, antivirals, and antibiotics against tick-borne pathogens;
  • Novel approaches to the diagnosis and therapy of tick-borne diseases;
  • Virtuous examples of multidisciplinary collaboration in a One Health perspective in the case management of tick-borne pathogens.

Dr. Giovanni Sgroi
Guest Editor

Dr. Kandai Doi
Guest Editor Assistant

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Keywords

  • public health
  • ticks
  • tick-borne disease
  • tick-borne pathogens

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Published Papers (1 paper)

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Research

18 pages, 1644 KiB  
Article
Molecular Typing of Tick-Borne Pathogens in Ixodids of Bosnia and Herzegovina
by Ina Hoxha, Jovana Dervović, Margarida Ruivo, Michiel Wijnveld, Adelheid G. Obwaller, Bernhard Jäger, Martin Weiler, Julia Walochnik, Edwin Kniha and Amer Alić
Microorganisms 2025, 13(5), 1054; https://doi.org/10.3390/microorganisms13051054 - 30 Apr 2025
Abstract
Ticks are key vectors of zoonotic pathogens, and their expanding distribution in Europe heightens public health concerns. In Bosnia and Herzegovina, while tick distribution is well documented, molecular data on tick-borne pathogens remain limited. This study aimed to illustrate the presence and diversity [...] Read more.
Ticks are key vectors of zoonotic pathogens, and their expanding distribution in Europe heightens public health concerns. In Bosnia and Herzegovina, while tick distribution is well documented, molecular data on tick-borne pathogens remain limited. This study aimed to illustrate the presence and diversity of these pathogens, focusing on areas with high human activity. Ticks (n = 556) were collected in April 2022 from eight diverse locations, including urban parks, private properties, and rural sites. PCR-based screening was employed to detect Anaplasmataceae, Borrelia, Francisella, Piroplasmida, Rickettsia, and tick-borne encephalitis virus (TBEV), with subsequent sequencing to confirm results. Further characterization of Borrelia burgdorferi sensu lato was achieved via reverse line blotting (RLB) hybridization and sequencing. Ixodes ricinus was the most prevalent species, followed by Dermacentor marginatus and D. reticulatus. Our analysis revealed an overall infection rate of 22.1% in questing ticks, with Rickettsia spp. and Borrelia spp. predominating. Notably, seven Borrelia species were identified in I. ricinus, alongside Anaplasma phagocytophilum, Rickettsia helvetica, and R. monacensis, with co-infections mainly observed in peri-urban areas. This study provides the first molecular evidence of multiple tick-borne pathogens in the region, underscoring the need for further surveillance and risk assessment of tick-borne diseases in the region. Full article
(This article belongs to the Special Issue Ticks and Threats: Insights on Tick-Borne Diseases)
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