Virulence-Associated Genes, Pathogenesis and Immunoevasion Mechanisms of African Swine Fever Virus
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Veterinary Microbiology".
Deadline for manuscript submissions: closed (30 April 2026) | Viewed by 2010
Special Issue Editor
Interests: classical swine fever (CSF); African swine fever (ASF); porcine reproductive and respiratory syndrome (PRRS); porcine pseudorabies (PPV); porcine circovirus (PCV); emerging viral diseases of swine; vaccines
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Special Issue Information
Dear Colleagues,
African swine fever (ASF) is a highly lethal viral disease affecting domestic pigs and wild suids, causing significant economic losses worldwide. The causative agent, African swine fever virus (ASFV), is a large, double-stranded DNA virus with a complex genome encoding numerous virulence-associated genes that are critical for viral replication, pathogenesis, and immune evasion.
This Special Issue aims to showcase cutting-edge research and reviews on ASFV virulence, host–pathogen interactions, and immunoevasion mechanisms. Topics of interest include the following:
- Identification and functional characterization of ASFV virulence-associated genes.
- Molecular mechanisms of ASFV-induced pathogenesis and tissue tropism.
- Viral strategies to evade innate and adaptive immune responses.
- Host factors influencing susceptibility, disease progression, and immune defense.
- Development of antiviral strategies and vaccine candidates targeting virulence and immune evasion.
- Advanced methodologies in ASFV genomics, transcriptomics, and proteomics related to pathogenicity.
We welcome original research articles, short communications, and comprehensive reviews that provide novel insights into ASFV biology, enhance understanding of virus–host interactions, and contribute to the development of effective control and prevention strategies against African Swine Fever.
Dr. Lihua Wang
Guest Editor
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Keywords
- African swine fever
- African swine fever virus
- virulence-associated gene
- pathogenesis
- immunoevasion
- antiviral strategy
- vaccine
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