Human Infectious Diseases, Second Edition

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Public Health Microbiology".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 250

Special Issue Editor


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Guest Editor
Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, USA
Interests: molecular epidemiology; genomic epidemiology; phylogenomics; microbiology; virology; phylogeny; bioinformatics; molecular microbiology; infectious diseases; public health
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Special Issue Information

Dear Colleagues,

This Special Issue is the continuation of our previous Special Issue, entitled “Human Infectious Diseases

The Special Issue offers a comprehensive exploration of the multifaceted landscape of infectious diseases, presenting a collection of articles that delve into the understanding, management, and prevention of a diverse array of infectious agents that impact global health.

This Special Issue encompasses a wide range of topics, including the epidemiology of infectious diseases, emerging and re-emerging pathogens, innovative diagnostic tools, treatment advancements, and the impact of infectious diseases on vulnerable populations. Furthermore, it addresses the intersection of infectious diseases with other public health challenges, such as antimicrobial resistance, vaccine hesitancy, and the influence of environmental factors.

Through the dissemination of cutting-edge research, clinical insights, and epidemiological perspectives, this Special Issue serves as a vital resource for healthcare professionals, researchers, and policymakers. It provides a platform for the exchange of knowledge and strategies aimed at combating existing infectious threats and preparing for future challenges in the realm of infectious diseases.

In conclusion, “Infectious Diseases” provides a holistic overview of the current state of infectious diseases globally, offering valuable insights that contribute to the ongoing efforts to understand, manage, and mitigate the impact of infectious agents, ultimately working towards the betterment of public health worldwide.

Dr. Eleonora Cella
Guest Editor

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Keywords

  • human
  • infectious diseases
  • public health

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Published Papers (1 paper)

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Review

15 pages, 720 KiB  
Review
Brevibacterium Species Infections in Humans—A Narrative Review
by Takis Panayiotou, Anastasia Vasilopoulou, Stella Baliou, Andreas G. Tsantes and Petros Ioannou
Microorganisms 2025, 13(5), 1097; https://doi.org/10.3390/microorganisms13051097 - 9 May 2025
Viewed by 206
Abstract
Brevibacterium species are Gram-positive, non-sporulating, coryneform, aerobic rods that are catalase positive and exhibit a distinctive transition from diptheroid to coccoid morphology during culture. Infections by these species are seldom identified. Objective: This narrative review aims to present all the reported cases of [...] Read more.
Brevibacterium species are Gram-positive, non-sporulating, coryneform, aerobic rods that are catalase positive and exhibit a distinctive transition from diptheroid to coccoid morphology during culture. Infections by these species are seldom identified. Objective: This narrative review aims to present all the reported cases of Brevibacterium spp. infections in humans, focusing on data about epidemiology, antimicrobial resistance, antimicrobial treatment, and mortality. A narrative review based on a literature search of PubMed/MedLine and Scopus databases was performed. In total, 41 studies providing data on 42 patients with Brevibacterium spp. infections were included in the present analysis. The median age was 48 years, while 57.5% were male. The presence of a central venous catheter and malignancy, and end-stage renal disease on peritoneal dialysis were the main predisposing factors. Bacteremia was the most common type of infection, with peritoneal dialysis-associated infections being the second most common. B. casei was the most commonly identified species. Microbial identification required the use of advanced molecular techniques, such as 16s rRNA sequencing or matrix-assisted laser desorption/ionization time of flight mass spectrometry in most cases. Brevibacterium spp. was highly resistant to the combination of trimethoprim with sulfamethoxazole, clindamycin, and common beta-lactams. The most commonly used antimicrobials were vancomycin and aminoglycosides. The mortality was about 10%. Clinicians and laboratory personnel should consider this pathogen in the differential diagnosis in patients with malignancy or peritoneal dialysis-associated peritonitis. Vancomycin should be used for empirical treatment and while antimicrobial susceptibility testing results are pending. Full article
(This article belongs to the Special Issue Human Infectious Diseases, Second Edition)
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