Neural Microelectrodes: Design, Integration, and Applications
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B：Biology and Biomedicine".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 19
Special Issue Editors
Interests: neural stimulation and recording; thin-film materials; chronic implants; implant system integration; implantable encapsulation
Interests: basic and translational neural interfaces; (Bio)MEMS; harsh environment sensors; thin film materials; microfabrication; materials characterization; applied surface science; electronic materials; solar cells
Special Issue Information
Dear Colleagues,
Microelectrode arrays serve as critical interfaces between biological systems and electronic devices, enabling the recording and stimulation of neural activity with high spatial and temporal precision. Over the past decades, they have played a foundational role in neuroscience research, neuroprosthetics, and brain–machine interfaces. With recent advances in materials science, microfabrication, and circuit integration, the next generation of microelectrode arrays offers unprecedented capabilities—including higher channel counts, improved biocompatibility, and enhanced mechanical flexibility. These innovations are driving a shift from basic research tools toward clinically and commercially viable technologies, opening new possibilities in both understanding and modulating complex neural systems.
This Special Issue aims to highlight recent advances in the application of next-generation microelectrode arrays for neural interfacing. As microelectrode technologies continue to evolve in terms of resolution, flexibility, biocompatibility, and scalability, their role in both fundamental neuroscience and translational neurotechnology is rapidly expanding.
We welcome submissions that explore the design and deployment of advanced microelectrode arrays in real-world experimental or clinical settings. Topics of interest include, but are not limited to, novel electrode architectures, electronics integration systems including advances in headstage designs, multi-modal integration, packaging, chronic implantation strategies, system-level demonstrations of functionality in neural recording or stimulation, and studies that translate microfabrication innovations into practical, high-performance neural interfaces, as well as those that validate next-generation arrays in vivo or in vitro. Contributions describing application-driven engineering solutions—spanning device characterization, data acquisition, and interface optimization—are strongly encouraged.
Dr. Felix Deku
Dr. Loren Rieth
Guest Editors
Manuscript Submission Information
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Keywords
- neural engineering
- microelectrode arrays
- high channel neural systems
- open source neurotechnology
- flexible biointerfaces
- signal acquisition
- chronic implantation
- hardware–software co-design
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