Special Issue "Metabolomics-Driven Biotechnology"
Deadline for manuscript submissions: closed (31 October 2019).
Interests: Flux Balance Analysis; Dynamic Modeling; Bioprocess Development
Bio-productions of useful compounds including foods, fermentation beverages, pharmaceuticals, chemicals, and fuels have been performed around the world. Metabolism is a sequence of chemical reactions in cells, and is the most important phenotype directly related to cellular activities. Redox and co-factor balance in the metabolism is also important to effectively increase the metabolic flow to target compounds. Marker metabolites are very useful to diagnose diseases in many medial applications. Precise and accurate analyses of metabolites and the development of control methods for the metabolism are key issues in biotechnology.
Recent big advances in comprehensive and specific analysis technology—including mass spectrometry and NMR—and in information technology with big metabolomics data are providing a new concept for “metabolomics-driven biotechnology”. This Special Issue of Metabolites is dedicated not only to the new analytical techniques, but also to the metabolic engineering strategies driven by metabolomics data. The topics of the Special Issue include cutting edge experimental and computational researches in the related area: target and non-target metabolome analyses, isotope labeling techniques, metabolic flux analysis, identification techniques for important genes to confer the superior phenotypes of cells, genome-wide and local metabolic modeling with static and dynamic metabolism data, and applications of metabolome analysis to the development of bio-production processes and medical treatments.
Prof. Hiroshi Shimizu
Dr. Yoshihiro Toya
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- 13C Metabolic Flux Analysis
- Flux Balance Analysis
- Kinetic Modelling
- Flux Analysis in Mammalian Cells