Role of Microbiome and Its Metabolites in Non-communicable Diseases
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Microbiology and Ecological Metabolomics".
Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 310
Special Issue Editor
Interests: human microbiome; gut microbiome; microbial ecology; microbiome–host interaction; microbiome-based intervention; microbiome modulation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The human gut microbiome has co-evolved with its host in a mutualistic relationship, providing key physiological functions aimed at maintaining the physiological state of health. Following the metabolism of dietary and/or host-derived compounds, the gut microbiome has the potential to produce a wide range of small bioactive molecules that exert a strong influence on multiple aspects of human physiology, from energy balance and metabolic regulation to the development and functioning of the immune, endocrine and nervous systems.
To date, multiple non-communicable diseases, such as metabolic syndrome, obesity, diabetes and cardiovascular and hepatic diseases, have been associated with impaired microbial layouts commonly known as dysbiosis.
Despite recent advances achieved through the integration of multi-omics data, the actual role of human microbiomes in the pathological context, possible causal relationships and underlying mechanisms have not yet been fully elucidated. In-depth studies of these aspects could help in developing increasingly effective and personalized microbiome-based intervention strategies, both for the prevention and treatment of non-communicable diseases.
This Special Issue aims to collect original articles and literature reviews focused on deepening knowledge on the mechanisms underlying the interaction between the microbiome and its metabolites on the health status of the host, with a particular focus on non-communicable diseases and the ways they can be modulated for the management or prevention of chronic conditions.
Dr. Monica Barone
Guest Editor
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Keywords
- gut microbiota
- non-communicable diseases
- metabolic syndrome
- obesity
- diabetes
- cardiovascular disease
- microbial metabolites
- microbial bioactive compounds
- intervention strategies
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