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Special Issue "Advances in Cellular Metabolomics"
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Cell Metabolism".
Deadline for manuscript submissions: closed (15 March 2021) | Viewed by 4403
Special Issue Editors
Interests: metabolomics; small molecule analysis; separation science; hyphenated mass spectrometry; sample preparation for metabolomics; cancer
Special Issues, Collections and Topics in MDPI journals
Interests: metabolomics; hyphenated mass spectrometry; cancer metabolism; tracing analysis
Special Issue Information
Shifts in cellular function are often accompanied by alterations of cellular metabolism, and numerous links to pathology, carcinogenesis and the immune response have been identified in recent years. A prominent example is the altered metabolism in cancer cells to meet the increased energy need and the requirement for cellular building blocks. Metabolic profiling and fingerprinting using various instrumental set ups have evolved as valuable tools for studying metabolism and tremendously increased our knowledge on cellular metabolism. Both targeted and untargeted approaches, however, only reflect a cell’s metabolic state, e.g., a metabolite pool size at the time point of sample collection. To gain further insights, tracing and flux analyses using stable-isotope-labeled nutrients are used to reveal changes in pathway activities and contributions. These experiments are typically performed with cells in culture.
Over the past years, huge progress has been made in the field of cellular metabolomics, including sample preparation and technical improvements, such as ion mobility-MS, single cell analysis and imaging techniques together with new algorithms and biostatistics tools to handle the data sets. This Special Issue of Metabolites “Advances in Cellular Metabolomics” is dedicated to these developments that have resulted in new insights into the interplay of cellular function and metabolism gained from the comprehensive analysis of cellular metabolites. Reviews and research manuscripts dealing with these and related issues are highly welcomed.
Dr. Katja Dettmer-Wilde
Dr. Raffaela Berger
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- (Un-)targeted metabolomics
- Metabolic flux and tracer analysis
- Multivariate biostatistics analysis
- Cell metabolism
- Enantioselective analysis