Nutritional Intervention and Metabolic Health: Carbohydrates and Keto Diet
A Special Issue of Metabolites (ISSN 2218-1989) belonging to the section "Nutrition and Metabolism".
Deadline for manuscript submissions: 15 March 2027 | Viewed by 812
Editor
Interests: type 2 diabetes mellitus; diet; glycaemic control; insulin sensitivity; metabolic health; dietary interventions; nutritional strategies; diabetes management; lifestyle factors; T2DM prevention
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The optimal macronutrient composition for maintaining metabolic health remains a subject of active scientific discussion, particularly regarding the comparative effects of low-fat and high-fat ketogenic diets (KDs). Recent evidence presents mixed outcomes. A 2023 umbrella review reported improvements in glycaemic control, weight management, and other cardiometabolic markers with KDs, but also highlighted an increase in low-density lipoprotein (LDL) cholesterol. Similarly, a 2022 meta-analysis observed elevated total and LDL cholesterol in individuals following very-low-carbohydrate diets compared to control groups. These findings emphasise the complex relationship among carbohydrate restriction, lipid metabolism, and long-term metabolic outcomes.
This Special Issue aims to examine how variations in carbohydrate intake and ketogenic dietary patterns influence glucose and lipid metabolism, insulin resistance, and cardiometabolic risk. We welcome studies addressing obesity, type 2 diabetes, and cardiovascular disease, as well as research exploring gut microbiota interactions and their role in metabolic regulation. Multi-omics approaches integrating genetic, epigenetic, and microbial determinants are encouraged. By combining molecular insights with clinical evidence, this Special Issue seeks to advance personalised nutrition strategies that promote metabolic resilience and support the prevention of chronic metabolic disorders.
Dr. Louise Lu
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metabolic health
- carbohydrate metabolism
- ketogenic diet
- personalized nutrition
- glycaemic control
- insulin sensitivity
- lipid profiles
- gut microbiome
- nutrient-sensing pathways
- epigenetic modifications
- personalized postprandial glucose response
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