Nutritional and Metabolic Regulation for One Health Across the Lifespan

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: 31 May 2026

Special Issue Editor


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Guest Editor
School of Medicine, Zhejiang University, Hangzhou 310058, China
Interests: nutrition; metabolism; trace elements; diabetes; aging
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Special Issue Information

Dear Colleague,

Nutrition and metabolism are fundamental to human health throughout the lifespan and play a pivotal role in the interconnected wellbeing of humans, animals, and the environment under the One Health framework. The regulation of nutritional and metabolic processes influences growth, immune resilience, and disease susceptibility, while imbalances contribute to chronic, infectious, and degenerative conditions. Integrating health promotion with ecological sustainability, the One Health approach encourages a systems-level understanding of how nutrition and metabolism shape health and disease across individual and population levels.

This Special Issue aims to advance interdisciplinary research on nutritional and metabolic regulation for One Health across the lifespan. We welcome submissions on research across various diseases, including obesity, diabetes, cardiovascular diseases, fatty liver, cancer, neurodegenerative diseases, autoimmune diseases, infectious diseases, and other conditions related to nutrition and metabolism. The topics covered include, but are not limited to, studies on nutritional interventions for disease prevention and management, mechanisms by which nutrients and metabolites regulate pathological processes, animal models for nutrition and disease, methodologies for characterizing metabolic status in disease, and causal inference between nutritional or metabolic factors and diseases.

In addition, we particularly encourage research that employs multi-omics analyses, gut microbiome studies, artificial intelligence, and multi-level and multidimensional analytical frameworks to reveal how nutritional and metabolic factors interact across biological and environmental contexts. Work exploring precision nutrition strategies tailored to different life stages, or integrating causal inference and systems biology, is also highly welcome. By combining mechanistic insights with innovative methodologies, this Special Issue seeks to inform evidence-based nutrition, promote disease prevention, and advance sustainable health within the One Health paradigm.

Dr. Xinhui Wang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nutrition
  • metabolism
  • one health
  • lifespan
  • artificial intelligence
  • metabolite
  • microbiome
  • precision nutrition
  • causal inference
  • multi-omics

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Published Papers

This special issue is now open for submission.
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