Climate Change-Related Stresses and Plant Metabolism

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Plant Metabolism".

Deadline for manuscript submissions: 14 July 2025 | Viewed by 227

Special Issue Editor


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Guest Editor
School of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA 24061, USA
Interests: plant metabolomics; digital agriculture and plant stress phenotyping; ma-chine learning; controlled environment agriculture and space biology; crop improvement

Special Issue Information

Dear Colleagues,

Climate change imposes various combinations of biotic and abiotic stresses on plants, which can disrupt photosynthesis, nutrient uptake, and increased susceptibility to pests and pathogens, thus negatively impacting plant growth.  Due to changes in environmental conditions, plants are often exposed to new stresses they have not encountered before, so that they may lack the relevant protective mechanisms. These stresses can significantly alter plant metabolism, reducing agricultural productivity and biodiversity. Understanding these impacts and implementing novel stress phenotyping and crop improvement tools is crucial for developing resilient crop species and sustainable agricultural practices. For this Special Issue, we encourage submitting original and review articles on any aspect of the topic relevant to climate change-related biotic and/or abiotic stresses in the context of plant metabolism and its regulation. These aspects may include, but are not limited to, investigating:

  1. Effects of individual and combined stresses on plant metabolomes and/or multi-omes;
  2. Effects of soil health on plant metabolomes and stress tolerance;
  3. How plants produce and use core and specialized metabolites to cope with stress;
  4. Metabolic and signaling pathways and their components associated with stress tolerance,

as well as developing novel approaches and methods for:

  1. Plant metabolomics and multi-omics;
  2. Plant stress phenotyping and machine learning;
  3. Identifying and manipulating genes and metabolic and signaling pathways associated with stress tolerance;
  4. Creating climate-resilient crops that can withstand multiple climate-related stresses.

Dr. Eva Collakova
Guest Editor

Manuscript Submission Information

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Keywords

  • plant physiology and metabolism
  • climate change-related stresses
  • multi-omics approaches
  • plant stress phenotyping
  • crop improvement

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Published Papers (1 paper)

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Review

32 pages, 1153 KiB  
Review
Unlocking Plant Resilience: Metabolomic Insights into Abiotic Stress Tolerance in Crops
by Agata Głuchowska, Bartłomiej Zieniuk and Magdalena Pawełkowicz
Metabolites 2025, 15(6), 384; https://doi.org/10.3390/metabo15060384 - 9 Jun 2025
Viewed by 33
Abstract
Background/Objectives: In the context of accelerating climate change and growing food insecurity, improving crop resilience to abiotic stresses such as drought, salinity, heat, and cold is a critical agricultural and scientific challenge. Understanding the biochemical mechanisms that underlie plant stress responses is essential [...] Read more.
Background/Objectives: In the context of accelerating climate change and growing food insecurity, improving crop resilience to abiotic stresses such as drought, salinity, heat, and cold is a critical agricultural and scientific challenge. Understanding the biochemical mechanisms that underlie plant stress responses is essential for developing resilient crop varieties This review aims to provide an integrative overview of how metabolomics can elucidate biochemical mechanisms underlying stress tolerance and guide the development of stress-resilient crops. Methods: We reviewed the recent literature on metabolomic studies addressing abiotic stress responses in various crop species, focusing on both targeted and untargeted approaches using platforms such as nuclear magnetic resonance (NMR), liquid chromatography–mass spectrometry (LC-MS), and gas chromatography–mass spectrometry (GC-MS). We also included emerging techniques such as capillary electrophoresis–mass spectrometry (CE-MS), ion mobility spectrometry (IMS-MS), Fourier transform infrared spectroscopy (FT-IR), and data-independent acquisition (DIA). Additionally, we discuss the integration of metabolomics with transcriptomics and physiological data to support system-level insights. Results: The reviewed studies identify common stress-responsive metabolites, including osmoprotectants, antioxidants, and signaling compounds, which are consistently linked to enhanced tolerance. Novel metabolic biomarkers and putative regulatory hubs are highlighted as potential targets for molecular breeding and bioengineering. We also address ongoing challenges related to data standardization and reproducibility across analytical platforms. Conclusions: Metabolomics is a valuable tool for advancing our understanding of plant abiotic stress responses. Its integration with other omics approaches and phenotypic analyses offers promising avenues for improving crop resilience and developing climate-adaptive agricultural strategies. Full article
(This article belongs to the Special Issue Climate Change-Related Stresses and Plant Metabolism)
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