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Metabolites
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Advances in Mass Spectrometry for Plant Metabolite Analysis: Techniques and...
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Advances in Mass Spectrometry for Plant Metabolite Analysis: Techniques and Applications

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Plant Metabolism".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 1232

Special Issue Editors

Dr. Mila Radan

E-Mail Website
Guest Editor
Department of Biochemistry, Faculty of Chemistry and Technology, University of Split, 21000 Split, Croatia
Interests: metabolomics
Dr. Prakash Babu Adhikari

E-Mail Website
Guest Editor
Biotechnology and Bioscience Research Center, Nagoya University, Nagoya 464-8601, Japan
Interests: plant metabolic engineering; plant breeding; gametophytic mutants screening; characterization

Special Issue Information

Dear Colleagues,

We are excited to share with you an opportunity to contribute to this Special Issue titled "Advances in Mass Spectrometry for Plant Metabolite Analysis: Techniques and Applications" in the open access journal Metabolites. Metabolites has become a recognized journal in the field of metabolomics, with an Impact Factor of 3.4 and a CiteScore of 5.7. We aim to highlight recent developments and innovative research in the field of plant metabolomics, focusing particularly on mass spectrometry techniques.

This Special Issue will explore the latest advancements in mass spectrometry for analyzing plant metabolites. Our goal is to emphasize practical applications that enhance our understanding of plant metabolism, improve crop quality, and support sustainable agricultural practices.

We welcome contributions on a wide range of topics, including, but not limited to, the following:

  • Identification, structure elucidation, and quantification of metabolites in unicellular and multicellular organisms, encompassing lipidomics, cheminformatics, and computational chemistry methods.
  • Progress in biological sample preparation methods for biomarker and metabolic profiling studies.
  • Advances in data processing and analysis for low-molecular-weight metabolite detection, identification, and curation.
  • Experimental and computational advancements in metabolic flux analysis.
  • The downstream effects of genetic and environmental changes on metabolite levels and fluxes.
  • Computational methods to understand metabolic processes and networks.
  • Agricultural and industrial applications, including plant and microbial metabolomics.

We believe that your expertise and insights would be a valuable addition to this Special Issue. We encourage you to submit original research, comprehensive reviews, or insightful case studies that align with these themes and help advance the field of plant metabolomics. We are aiming for a tentative deadline of 31 December 2024 for manuscript submissions. Please feel free to reach out if you have any questions or need further information. We look forward to your contribution to this Special Issue.

Best regards,

Dr. Mila Radan
Dr. Prakash Babu Adhikari
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • mass spectrometry
  • plant metabolomics
  • biomarker discovery
  • metabolic networks: metabolic flux
  • MS data analysis
  • metabolic diseases

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

19 pages, 3267 KiB  
Article
Metabolomic Analysis of Maize Response to Northern Corn Leaf Blight
by Yingnan Gu, Bowei Yan, Ye Yang, Ying Huang, Xin Liu and Shubin Liu
Metabolites 2025, 15(2), 113; https://doi.org/10.3390/metabo15020113 - 10 Feb 2025
Viewed by 630
Abstract
Background: As a major food crop, maize is highly susceptible to pathogenic bacteria, which greatly reduces its yield and quality. Metabolomics reveals physiological and biochemical changes in organisms and aids in analyzing metabolic changes caused by various factors. Methods: This study utilized metabolomics [...] Read more.
Background: As a major food crop, maize is highly susceptible to pathogenic bacteria, which greatly reduces its yield and quality. Metabolomics reveals physiological and biochemical changes in organisms and aids in analyzing metabolic changes caused by various factors. Methods: This study utilized metabolomics to examine maize’s metabolic changes after NCLB infestation, aiming to uncover related pathways and potential biomarkers. The metabolite measurements were performed during the maize silking stage. Results: PCA showed an obvious dispersion between the treated and untreated groups. OPLS-DA identified 1274 differential metabolites, with 242 being downregulated (mainly phenolics and esters) and 1032 upregulated (primarily organic acids, amino acids, sugars, and derivatives). KEGG annotation revealed 50 affected metabolic pathways, and the biosynthesis of secondary metab-olites and amino acids was significantly enriched. Conclusions: We hypothesized that metabolic pathways related to sugar metabolism, proline metabolism, and jasmonic acid synthesis are associated with NCLB susceptibility. These findings provide critical insights into the metabolic responses of maize to biotic stress, offering a theoretical basis for future research on plant resistance mechanisms. Full article
(This article belongs to the Special Issue Advances in Mass Spectrometry for Plant Metabolite Analysis: Techniques and Applications)
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