Membranes for the Purification of Biotherapeutics
A special issue of Membranes (ISSN 2077-0375). This special issue belongs to the section "Membrane Applications for Other Areas".
Deadline for manuscript submissions: 30 August 2026 | Viewed by 163
Special Issue Editors
Interests: purification of biologics; affinity and multimodal ligands; membrane chromatography; membrane separation processes; analytical, pilot plant, and large-scale operations
Interests: membrane separation processes; membrane chromatography; mixed matrix membranes; protein purification; bioseparations; ultrafiltration; membrane bioreactors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue will highlight recent developments in the use of membranes for the purification and polishing of biologics, including, but not limited to, tangential flow filtration, diafiltration, ultrafiltration, microfiltration, and membrane chromatography. This includes the use of membranes in a flow-through mode for removing process and product impurities and in a bind-and-elute mode for product capture. We seek papers describing new ideas and membrane approaches for purifying a broad range of biologics, including antibodies, antibody fragments, peptides, viral vectors, and mRNA and DNA for gene therapies. Of particular interest are quantitative comparisons of membrane-based processes incorporating resin chromatography, as measured by process productivity, overall process times, process mass intensity, eCO2emissions, and applications of single-use technologies. We welcome papers on fundamental and practical advances, such as (1) new ion exchange; multimodal and other ligands; (2) new membrane structures, including cast and nonwoven fabric membranes; (3) modelling and mechanistic analyses of membrane performance; and (4) continuous operation and positioning of membranes in downstream processes to maximise efficiency and reduce capital and operating costs. Submissions should include academic studies demonstrating revolutionary approaches, as well as examples of recent industrial applications of membrane technologies.
Prof. Dr. Ruben G. Carbonell
Prof. Cristiana Boi
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Membranes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- membrane purification
- diafiltration
- tangential flow filtration
- microfiltration
- ultrafiltration
- membrane chromatography
- flow-through polishing and purification
- product capture
- multimodal ion exchange
- hydrophobic and affinity ligands for membranes
- modelling and continuous operation of membrane chromatography
- membrane purification of biologics
- antibodies
- antibody fragments
- viral vectors
- nucleotides
- comparison of membrane chromatography to column chromatography
- productivity
- process mass intensity
- eCO2emissions in membrane processes
- capital and operating costs of membranes vs. column chromatography
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