Special Issue "Men's Sexual Health"

A special issue of Medical Sciences (ISSN 2076-3271).

Deadline for manuscript submissions: 30 November 2019.

Special Issue Editor

Prof. Eric Chung
E-Mail Website
Guest Editor
Director at AndroUrology Centre for Sexual, Urinary and Reproductive Excellence Associate Professor of Surgery, University of Queensland, Brisbane, Queensland, Australia Macquarie University Hospital, Sydney, New South Wales, Australia
Interests: Male sexual and reproductive surgery; penile reconstruction and prosthesis surgery; stem cells; testosterone deficiency

Special Issue Information

Dear Colleagues,

Significant advances have been made in the field of men’s sexual health (MSH) in recent years. The introduction of new and novel technologies to diagnose and manage various sexual health conditions has revolutionised the ways in which we approach and provide evidence-based medicine healthcare for effective outcomes.
This Special Issue will address controversial areas as well as provide critical reviews of important topics in MSH. This Special Issue will feature short, focused reviews, including an update on the advances and challenges in the latest trends in MSH. The goals of publication are to deliver state-of-art information on emerging ideas as well as to reassess contemporary management strategies on key aspects of MSH.
I hope that this Special Issue will serve as an informative and enjoyable reference to readers on a diverse group of sexual medicine related topics.

We look forward to receiving your contributions.

Prof. Eric Chung
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medical Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Current limitations in medical therapy for Peyronie’s disease: Should medical therapy be offered?
  • Penile prosthesis implant: Addressing the current limitations of conventional medical therapy in erectile dysfunction
  • Sexual health, cardiovascular risk modification, and exercise program: Concept in prostate cancer survivorship
  • Sexuality, sexual health, and ageing population
  • Imaging modalities in prostate cancer: Revolutionizing the way we image prostate cancer
  • Low-intensity shockwave therapy for men with erection dysfunction: From concept to clinical applications
  • Genetic markers for prostate cancer diagnosis and prognosis: Improving the detection and management
  • Novel and standard imaging studies for Peyronie’s disease: Imaging the penis
  • Prostate cancer survivorship on erectile and sexual dysfunction: Evaluating the “real data” and current strategies to penile rehabilitation

Published Papers (6 papers)

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Review

Open AccessReview
Sexuality in Ageing Male: Review of Pathophysiology and Treatment Strategies for Various Male Sexual Dysfunctions
Med. Sci. 2019, 7(10), 98; https://doi.org/10.3390/medsci7100098 - 20 Sep 2019
Abstract
Sexual function among older men is often thought to decrease as part of normal ageing biology despite the fact that sexuality remains an important issue in the elderly. Sexual dysfunction in the aged male is likely multifactorial in nature, with the development and/or [...] Read more.
Sexual function among older men is often thought to decrease as part of normal ageing biology despite the fact that sexuality remains an important issue in the elderly. Sexual dysfunction in the aged male is likely multifactorial in nature, with the development and/or progression of medical comorbidities often resulting in decline in male sexual function and poor treatment response. At present, sexual dysfunction in the ageing male is poorly investigated and understood, and current treatment strategies aim at improving sexual desire and erectile function with limited data on ejaculatory and orgasmic dysfunctions. In addition, men are often reticent to seek help for health concerns including sexual dysfunction. The following article provides a narrative review of strategies to address various aspects of sexual dysfunction in the ageing male. Clinicians need to be educated to be sensitive when discussing sexuality issues among older men and to present practical solutions that take into account individual and cultural differences. Full article
(This article belongs to the Special Issue Men's Sexual Health)
Open AccessReview
Medical Management of Peyronie’s Disease: Review of the Clinical Evidence
Med. Sci. 2019, 7(9), 96; https://doi.org/10.3390/medsci7090096 - 18 Sep 2019
Abstract
Peyronie’s disease is a condition that causes abnormal healing of the tunica albuginea, causing penile curvature. It is difficult to treat and its management is continuing to evolve. Proposed non-surgical treatments have included oral, topical, intralesional, extracorporeal shockwave, and traction therapy. The study [...] Read more.
Peyronie’s disease is a condition that causes abnormal healing of the tunica albuginea, causing penile curvature. It is difficult to treat and its management is continuing to evolve. Proposed non-surgical treatments have included oral, topical, intralesional, extracorporeal shockwave, and traction therapy. The study of Peyronie’s disease is made difficult by heterogeneity in the timing of presentation, severity and characteristics of deformity, and associated complaints. Moreover, meta-analyses of studies are difficult due to inconsistencies across study endpoints and the duration of treatments. This article reviews the current clinical evidence and guideline recommendations, with a focus on an improvement in penile curvature. Full article
(This article belongs to the Special Issue Men's Sexual Health)
Open AccessReview
A Review of Current and Emerging Therapeutic Options for Erectile Dysfunction
Med. Sci. 2019, 7(9), 91; https://doi.org/10.3390/medsci7090091 - 29 Aug 2019
Abstract
Contemporary treatment algorithms for erectile dysfunction (ED) involve the use of medical therapies such as phosphodiesterase type 5 (PDE5) inhibitors and intracavernosal injection therapy of vasoactive agents, as well as vacuum erection devices and penile prosthesis implants in medically refractory cases. However, the [...] Read more.
Contemporary treatment algorithms for erectile dysfunction (ED) involve the use of medical therapies such as phosphodiesterase type 5 (PDE5) inhibitors and intracavernosal injection therapy of vasoactive agents, as well as vacuum erection devices and penile prosthesis implants in medically refractory cases. However, the current therapeutic options only address the symptoms of ED and not the underlying pathogenesis that results in ED. Newer and novel ED therapies aspire to reverse ED conditions by preventing cavernosal fibrosis, promoting endothelial revascularization and modulating various neuro-hormonal pathways. Regenerative therapeutic strategies such as low-intensity shock wave, gene and cellular-based therapies, and penile transplants are designed to improve penile hemodynamics and revitalize the cavernosal smooth muscle to mitigate and/or reverse underlying ED. This state-of-art article evaluates current and emerging therapeutic options for ED. Full article
(This article belongs to the Special Issue Men's Sexual Health)
Open AccessReview
Erectile Dysfunction: A Primer for in Office Management
Med. Sci. 2019, 7(9), 90; https://doi.org/10.3390/medsci7090090 - 29 Aug 2019
Abstract
Introduction: Optimizing erectile dysfunction (ED) remains a clinically significant endeavor as insufficient outcomes from oral, injectable and even surgical approaches to treatment remain less than ideal. In this report, we integrate evolving knowledge and provide an algorithmic approach for the clinician to fine-tune [...] Read more.
Introduction: Optimizing erectile dysfunction (ED) remains a clinically significant endeavor as insufficient outcomes from oral, injectable and even surgical approaches to treatment remain less than ideal. In this report, we integrate evolving knowledge and provide an algorithmic approach for the clinician to fine-tune management. Methods: We performed a PubMed and Medline search of Erectile Dysfunction treatment optimization, enhanced patient efficacy for ED, and why men fail ED treatment. All relevant papers for the past two decades were reviewed. Results: Establishing the goals and objectives of the patient and partner while providing detailed instructions for treatment can minimize failures and create an environment that allows treatment optimization. A thorough work-up may identify reversible or contributing causes. We identified several areas where treatment of ED could be optimized. These include; management of associated medical conditions, lifestyle improvements, PDE5 inhibitor prescription strategies, management of hypogonadism and the initiation of intracavernosal injection therapy (ICI). Conclusions: In our view, once a man presents for help to the clinician, use of the simple strategies identified in this review to optimize the tolerability, safety and effectiveness of the selected treatment should result in enhanced patient and partner satisfaction, with improved outcomes. Full article
(This article belongs to the Special Issue Men's Sexual Health)
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Open AccessReview
Contemporary and Novel Imaging Studies for the Evaluation of Erectile Dysfunction
Med. Sci. 2019, 7(8), 87; https://doi.org/10.3390/medsci7080087 - 09 Aug 2019
Abstract
Traditionally, it was thought that the pathogenesis of erectile dysfunction (ED) can be divided into psychological and organic factors. However, recent literature supports the development and progression of ED due to multidimensional alterations of a complex interplay of central and peripheral systems, from [...] Read more.
Traditionally, it was thought that the pathogenesis of erectile dysfunction (ED) can be divided into psychological and organic factors. However, recent literature supports the development and progression of ED due to multidimensional alterations of a complex interplay of central and peripheral systems, from neural cognitive and efferent networks to loco-regional neuro-hormonal factors which are responsible for impaired penile vascular hemodynamics and ensuing lack of, or suboptimal, blood flow into the penis and/or veno-occlusive dysfunction. It is recognised that ED is strongly correlated with cardiovascular health and published clinical guidelines advocate screening for cardiovascular and metabolic risk factors in men presenting with ED. Over the past few decades, various imaging modalities have been developed and utilised to provide objective evaluation for ED to better characterise the state of penile health and exclude psychogenic components. The following article evaluates current and emerging imaging diagnostic tools for ED. Full article
(This article belongs to the Special Issue Men's Sexual Health)
Open AccessReview
The Use of MRI and PET Imaging Studies for Prostate Cancer Management: Brief Update, Clinical Recommendations, and Technological Limitations
Med. Sci. 2019, 7(8), 85; https://doi.org/10.3390/medsci7080085 - 05 Aug 2019
Abstract
Multi-parametric magnetic resonance imaging (mpMRI) and positron emission tomography (PET) using prostate-specific membrane antigen (PSMA) targeting ligands have been adopted as a new standard of imaging modality in the management of prostate cancer (PCa). Technological advances with hybrid and advanced computer-assisted technologies such [...] Read more.
Multi-parametric magnetic resonance imaging (mpMRI) and positron emission tomography (PET) using prostate-specific membrane antigen (PSMA) targeting ligands have been adopted as a new standard of imaging modality in the management of prostate cancer (PCa). Technological advances with hybrid and advanced computer-assisted technologies such as MR/PET, MR/US, multi-parametric US, and robotic biopsy systems, have resulted in improved diagnosis and staging of patients in various stages of PCa with changes in treatment that may be considered “personalized”. Whilst newer clinical trials incorporate these novel imaging modalities into study protocols and as long-term data matures, patients should be made aware of the potential benefits and harm related to these technologies. Published literature needs to report longer-term treatment efficacy, health economic outcomes, and adverse effects. False positives and negatives of these imaging modalities have the potential to cause harm and the limitations of these technologies should be appreciated. The role of a multi-disciplinary team (MDT) and a shared-decision-making model are important to ensure that all aspects of the novel imaging modalities are considered. Full article
(This article belongs to the Special Issue Men's Sexual Health)
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