Next Article in Journal
Incidence and Prevalence of Polymyalgia Rheumatica (PMR): The Importance of the Epidemiological Context. The Italian Case
Next Article in Special Issue
Medical Management of Peyronie’s Disease: Review of the Clinical Evidence
Previous Article in Journal / Special Issue
Erectile Dysfunction: A Primer for in Office Management
Review

A Review of Current and Emerging Therapeutic Options for Erectile Dysfunction

by 1,2,3
1
AndroUrology Centre, Brisbane 4000, Queensland, Australia
2
University of Queensland, Princess Alexandra Hospital, Brisbane 4102, Queensland, Australia
3
Macquarie University Hospital, Sydney 2109, New South Wales, Australia
Med. Sci. 2019, 7(9), 91; https://doi.org/10.3390/medsci7090091
Received: 3 July 2019 / Revised: 20 August 2019 / Accepted: 23 August 2019 / Published: 29 August 2019
(This article belongs to the Special Issue Men's Sexual Health)
Contemporary treatment algorithms for erectile dysfunction (ED) involve the use of medical therapies such as phosphodiesterase type 5 (PDE5) inhibitors and intracavernosal injection therapy of vasoactive agents, as well as vacuum erection devices and penile prosthesis implants in medically refractory cases. However, the current therapeutic options only address the symptoms of ED and not the underlying pathogenesis that results in ED. Newer and novel ED therapies aspire to reverse ED conditions by preventing cavernosal fibrosis, promoting endothelial revascularization and modulating various neuro-hormonal pathways. Regenerative therapeutic strategies such as low-intensity shock wave, gene and cellular-based therapies, and penile transplants are designed to improve penile hemodynamics and revitalize the cavernosal smooth muscle to mitigate and/or reverse underlying ED. This state-of-art article evaluates current and emerging therapeutic options for ED. View Full-Text
Keywords: erectile dysfunction; phosphodiesterase type 5; intracavernosal injection; penile prosthesis implant; low-intensity shock wave; stem cell; gene therapy; platelet rich plasma; microvascular stent; penile transplant erectile dysfunction; phosphodiesterase type 5; intracavernosal injection; penile prosthesis implant; low-intensity shock wave; stem cell; gene therapy; platelet rich plasma; microvascular stent; penile transplant
MDPI and ACS Style

Chung, E. A Review of Current and Emerging Therapeutic Options for Erectile Dysfunction. Med. Sci. 2019, 7, 91. https://doi.org/10.3390/medsci7090091

AMA Style

Chung E. A Review of Current and Emerging Therapeutic Options for Erectile Dysfunction. Medical Sciences. 2019; 7(9):91. https://doi.org/10.3390/medsci7090091

Chicago/Turabian Style

Chung, Eric. 2019. "A Review of Current and Emerging Therapeutic Options for Erectile Dysfunction" Medical Sciences 7, no. 9: 91. https://doi.org/10.3390/medsci7090091

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop