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The Use of MRI and PET Imaging Studies for Prostate Cancer Management: Brief Update, Clinical Recommendations, and Technological Limitations

1
Department of Urology, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, QLD 4102 Australia
2
University of Queensland, St Lucia, QLD 4067, Australia
3
AndroUrology Centre, Brisbane, QLD 4000, Australia
*
Author to whom correspondence should be addressed.
Med. Sci. 2019, 7(8), 85; https://doi.org/10.3390/medsci7080085
Received: 3 July 2019 / Revised: 28 July 2019 / Accepted: 31 July 2019 / Published: 5 August 2019
(This article belongs to the Special Issue Men's Sexual Health)
Multi-parametric magnetic resonance imaging (mpMRI) and positron emission tomography (PET) using prostate-specific membrane antigen (PSMA) targeting ligands have been adopted as a new standard of imaging modality in the management of prostate cancer (PCa). Technological advances with hybrid and advanced computer-assisted technologies such as MR/PET, MR/US, multi-parametric US, and robotic biopsy systems, have resulted in improved diagnosis and staging of patients in various stages of PCa with changes in treatment that may be considered “personalized”. Whilst newer clinical trials incorporate these novel imaging modalities into study protocols and as long-term data matures, patients should be made aware of the potential benefits and harm related to these technologies. Published literature needs to report longer-term treatment efficacy, health economic outcomes, and adverse effects. False positives and negatives of these imaging modalities have the potential to cause harm and the limitations of these technologies should be appreciated. The role of a multi-disciplinary team (MDT) and a shared-decision-making model are important to ensure that all aspects of the novel imaging modalities are considered. View Full-Text
Keywords: prostate cancer; multi-parametric magnetic resonance imaging; prostate specific membrane antigen; positron emission tomography prostate cancer; multi-parametric magnetic resonance imaging; prostate specific membrane antigen; positron emission tomography
MDPI and ACS Style

Mansbridge, M.; Chung, E.; Rhee, H. The Use of MRI and PET Imaging Studies for Prostate Cancer Management: Brief Update, Clinical Recommendations, and Technological Limitations. Med. Sci. 2019, 7, 85.

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