Emerging Technologies in Lithotripsy: Challenges, Trends and Perspectives

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Urology & Nephrology".

Deadline for manuscript submissions: closed (20 March 2024) | Viewed by 1296

Special Issue Editor


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Guest Editor
Division of Urology, Cambridge Health Alliance, Cambridge, MA 02139, USA
Interests: endourology; nephrolithiasis; lithotripsy

Special Issue Information

Dear Colleagues,

Urolithiasis is one of the most common urological diseases and is increasing in prevalence worldwide. In the United States, the prevalence has increased to nearly 8.8% over the past 40 years (Scales 2012). In the United Kingdom, the lifetime prevalence of nephrolithiasis has increased from 7.14% to 14%, and in Japan, the incidence has been rising over the past 40 years as well (Rukin 2017; Turney 2011; Yasui 2008). Although intrarenal stones may be asymptomatic, many ultimately migrate and become obstructive. Ureteral and renal calculi can lead to symptoms involving severe abdominal and flank pain, nausea, and urinary tract problems.

Recent years have seen a plethora of new tools emerge for the management of renal calculi as well as variations on established techniques. In this Special Issue, Medicina seeks to explore and evaluate these new technologies including thulium lasers and new approaches to percutaneous nephrolithotomy. To that aim, we invite you to submit articles that review these new innovations.

Dr. Maria Ordonez
Guest Editor

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Keywords

  • holium
  • thulium
  • ureteroscopy
  • nephrolithiasis
  • nephrolithotomy

Published Papers (2 papers)

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Research

15 pages, 913 KiB  
Article
Percutaneous Nephrostomy versus Ureteral Stent for Severe Urinary Tract Infection with Obstructive Urolithiasis: A Systematic Review and Meta-Analysis
by Young Joon Moon, Dae Young Jun, Jae Yong Jeong, Seok Cho, Joo Yong Lee and Hae Do Jung
Medicina 2024, 60(6), 861; https://doi.org/10.3390/medicina60060861 (registering DOI) - 24 May 2024
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Abstract
Background and Objectives: The European Association of Urology guidelines on urolithiasis highlight the limited evidence supporting the superiority of percutaneous nephrostomy (PCN) over retrograde ureteral stent placement for the primary treatment of infected hydronephrosis secondary to urolithiasis. We, therefore, conducted a systematic [...] Read more.
Background and Objectives: The European Association of Urology guidelines on urolithiasis highlight the limited evidence supporting the superiority of percutaneous nephrostomy (PCN) over retrograde ureteral stent placement for the primary treatment of infected hydronephrosis secondary to urolithiasis. We, therefore, conducted a systematic review and meta-analysis comparing the effects of PCN and retrograde ureteral stent in patients with severe urinary tract infections secondary to obstructive urolithiasis. Materials and Methods: Meta-analyses were performed to compare four outcomes: time for the temperature to return to normal; time for the white blood cell (WBC) count to return to normal; hospital length of stay; and procedure success rate. After a full-text review, eight studies were identified as relevant and included in our systematic review and meta-analysis. Results: No significant difference was detected between PCN and retrograde ureteral stenting for the time for the temperature to return to normal (p = 0.13; mean difference [MD] = −0.74; 95% confidence interval [CI] = −1.69, 0.21; I2 = 96%) or the time for the WBC count to return to normal (p = 0.24; MD = 0.46; 95% CI = −0.30, 1.21; I2 = 85%). There was also no significant difference between methods for hospital length of stay (p = 0.78; MD = 0.45; 95% CI = −2.78, 3.68; I2 = 96%) or procedure success rate (p = 0.76; odds ratio = 0.86; 95% CI = 0.34, 2.20; I2 = 47%). Conclusions: The clinical outcomes related to efficacy did not differ between PCN and retrograde ureteral stenting for severe urinary tract infection with obstructive urolithiasis. Thus, the choice between procedures depends mainly on the urologist’s or patient’s preferences. Full article
11 pages, 626 KiB  
Article
Urolithiasis in Kidney Transplant Patients: A Multicenter KSER Research Series
by Kang Hee Shim, Kwi Bok Choi, Woong Bin Kim, Seung Woo Yang, Do Kyung Kim, Min Soo Choo, Doo Yong Chung, Hae Do Jung, Sin Woo Lee, Bum Soo Kim, Seung Hyun Jeon, Seok Ho Kang, Sunghyun Paick and Joo Yong Lee
Medicina 2024, 60(1), 132; https://doi.org/10.3390/medicina60010132 - 10 Jan 2024
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Abstract
Background and Objectives: Urolithiasis occurrence is uncommon in kidney transplantation patients, though it has serious implications, including acute kidney injury in the transplanted kidney. This study investigates the leading causes of urolithiasis in kidney transplantation patients, the diagnostic process, and the outcomes [...] Read more.
Background and Objectives: Urolithiasis occurrence is uncommon in kidney transplantation patients, though it has serious implications, including acute kidney injury in the transplanted kidney. This study investigates the leading causes of urolithiasis in kidney transplantation patients, the diagnostic process, and the outcomes of multimodal management. Materials and Methods: Data collection spanned from January 1997 to December 2021, involving kidney transplantation patients with urolithiasis from the database of the Korean Society of Endourology and Robotics (KSER) research committee. Analysis encompassed factors triggering urolithiasis, the diagnostic process, stone attributes, treatment methods, and outcomes. Results: Our analysis included 58 kidney transplantation patients with urolithiasis from eight medical centers. Of these patients, 37 were male and 4 had previous urolithiasis diagnoses. The mean age was 59.09 ± 10.70 years, with a mean duration from kidney transplantation to diagnosis of 76.26 ± 183.14 months. The most frequent method of stone detection was through asymptomatic routine check-ups (54.7%). Among the 58 patients, 51 underwent stone treatment. Notably, 95.3% of patients with ureter stones received treatment, a significantly higher rate than the 66.7% of patients with renal stones (p = 0.010). Success rates showed no significant differences between renal (70%) and ureter stone (78.0%) groups (p = 0.881). Conclusions: Urolithiasis in transplanted kidneys constitutes an acute condition requiring emergency intervention. Endo-urological interventions are effective for kidney transplantation patients with urolithiasis. To ensure prevention and early detection, diligent follow-up and routine imaging tests are necessary. Full article
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