Clinical Updates and Future Perspectives on Acute Myocardial Infarction
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Cardiology".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 865
Special Issue Editors
Interests: heart attack; atrial fibrillation; angioplasty; coronary angiography
Interests: echocardiography; electrophysiology; interventional cardiology; chronic coronary syndrome; myocardial infarction; arrhythmias; heart failure; infective endocarditis
Interests: coronary angiography; hypertension; PCI; atherosclerosis; myocardial infarction; acute myocardial infarction; chronic coronary syndrome; diabetology; peripheral atherosclerotic disease
Special Issue Information
Dear Colleagues,
This Special Issue of Medicina, titled "Clinical Updates and Future Perspectives on Acute Myocardial Infarction", explores the latest advancements in both the acute management and chronic care of acute myocardial infarction (AMI). Despite significant progress in diagnosis and treatment, AMI remains a leading cause of morbidity and mortality, requiring continuous innovation in reperfusion strategies, cardioprotective therapies, and secondary prevention approaches.
This Special Issue highlights recent breakthroughs in reperfusion therapy, including next-generation thrombolytics, advances in percutaneous coronary intervention (PCI), and hybrid revascularization techniques aimed at optimizing myocardial salvage and reducing infarct size. Additionally, it explores novel mechanical circulatory support (MCS) devices such as Impella, intra-aortic balloon pumps (IABPs), and extracorporeal membrane oxygenation (ECMO) for high-risk AMI patients and those with cardiogenic shock.
Emerging lipid-lowering and cardioprotective therapies such as bempedoic acid, PCSK9 inhibitors (PCSK9i), and GLP-1 receptor agonists (GLP-1 RA) are discussed for their potential to improve long-term cardiovascular outcomes. Advances in electrophysiological management, including bundle branch pacing (BBP) and cardiac contractility modulation (CCM), are explored as alternatives for improving post-AMI heart function.
This Special Issue also investigates the role of artificial intelligence and precision medicine in refining risk stratification and treatment personalization. Furthermore, regenerative and anti-inflammatory therapies offer promising prospects for myocardial repair and reducing post-AMI complications such as heart failure and arrhythmias.
By presenting these advancements, this Special Issue aims at equipping healthcare professionals with the latest knowledge and innovative strategies to enhance AMI management, improve survival rates, and reduce long-term complications.
Dr. Ciro Mauro
Dr. Fulvio Cacciapuoti
Guest Editors
Dr. Gerardo Carpinella
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- acute myocardial infarction
- early-phase management
- long-term cardiac care
- mechanical circulatory support
- intensive care
- lipid-lowering and cardioprotective therapies
- precision medicine and artificial intelligence in cardiology
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