Special Issue "Advances in Smart Nanocarriers for Targeted Drug Delivery"

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: 30 June 2021.

Special Issue Editors

Prof. Dr. Nicola Margiotta
E-Mail Website1 Website2
Guest Editor
Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, via E. Orabona 4, 70125 Bari, Italy
Interests: medicinal inorganic chemistry; organometallic chemistry; metal-based complexes; antitumor platinum drugs; drug delivery of antitumor drugs by inorganic nanocarriers
Special Issues and Collections in MDPI journals
Dr. Michele Iafisco
E-Mail Website
Guest Editor
Laboratory of Bioceramics and Bio-hybrid Composites, CNR - Institute of Science and Technology for Ceramics. Via Granarolo, 64 I-48018 FAENZA (RA), Italy
Interests: biomaterials; nanomedicine; bioceramics; biomineralization; calcium phosphates
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Conventional drug-delivery systems often reveal the problem of non-specific distribution and the uncontrolled release of drugs. This has led to the development of smart devices, often in the nano dimensions, specifically designed for drug delivery, that can occur in a spatially controlled manner and with a reduced dosage of drugs. Not all types of nanocarriers are sufficiently smart to be employed in drug delivery, with ideal candidates being those (i) carrying drugs specifically at the site of action, (ii) that are targeted by the unhealthy cell or tissue, and (iii) that are stimulus-responsive to releasing the drug payload.

The most reported smart nanocarriers include liposomes, dendrimers, micelles, meso-porous silica, gold nanoparticles, super paramagnetic iron-oxide, graphene, carbon nanotubes, quantum dots, etc. The smartness of a drug-delivering nanocarrier increases if the system is highly biocompatible and poorly toxic. Hence, accumulation of the nanocarrier in the vital organs followed by its degradation (if any) can lead to toxicity, which, ultimately, depends on the physico-chemical properties of the nanosystem (composition, shape, size, specific surface area, surface charge, etc.).

The development of smart nanocarriers to be applied in drug-delivery requires the collaboration of chemists, physicists, pharmacologists, and physicians who, in most cases, have different objectives. Therefore, we invite all those working in these fields to make a contribution (full papers, communications, and reviews) to this Special Issue entitled “Advances in Smart Nanocarriers for Targeted Drug Delivery”. This Special Issue represents a good opportunity for researchers around the world to disseminate different aspects of their work spanning from materials science to cell biology, biomolecular design, engineering, and medical physics.

Prof. Dr. Nicola Margiotta
Dr. Michele Iafisco
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • inorganic Nanocarriers
  • organic nanocarriers
  • drug delivery
  • liposomes
  • dendrimers
  • micelles
  • silica
  • gold nanoparticles
  • SPIONs
  • graphene
  • carbon nanotubes
  • quantum dots

Published Papers

This special issue is now open for submission.
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