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Special Issue "Non-viral Vectors for Cancer Therapy"

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (20 July 2023) | Viewed by 273

Special Issue Editors

Advanced Polymer Materials Group, Department of Bioresources and Polymer Science, University Politehnica of Bucharest, 060042 Bucharest, Romania
Interests: polymer; 3D printing; organ on-a-chip; biomaterial; nanoparticle; hydrogel; rheology
Special Issues, Collections and Topics in MDPI journals
Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1–7 Gh. Polizu Street, 011061 Bucharest, Romania
Interests: polymers; cancer management; drug delivery; polymeric nanoparticles; hydrogels; 3D printing; organ on-a-chip; polymer processing; additives for polymers

Special Issue Information

Dear Colleagues,

Cancer has many facets, and these are tackled by various methods including chemotherapy, radiotherapy, surgery, and immunotherapy. Cancer gene therapy refers to the transfer of nucleic acids into cancer cells and the surrounding tissue to cause cell death or slow the cancer growth. In this context, non-viral vectors show good results due to their low cost, safety, and availability. This Special Issue will focus on the recent developments regarding the use of various types of non-viral vectors for cancer and cancer gene management. Plasmid (pDNA), messenger RNA (mRNA), oligonucleotides, and RNA interference approaches (siRNA, shRNA, miRNA) are of great interest to be introduced into various vehicles such as polysaccharides (chitosan, alginate, pectin), proteins (silk fibroin, silk sericin), synthetic polymers (PLA, PLGA, PVA), and lipids (liposomes, lipid nanoparticles).

Polymers are one of the most versatile materials in the fight against cancer. They are easy to obtain, can be modified to better fit the application, and can be transformed into complex nanostructures with increased biocompatibility and endocytosis. Furthermore, polymers and polymeric systems can deliver drugs with tunable pharmacokinetics and circulation times. A special focus is on the polymeric materials which are stimuli-responsive, lipids, dendrimers, or macromolecules for intracellular delivery of drugs. Cancer involves a multiple stimuli approach, therefore, multi-stimuli responsiveness is very important to design and develop custom structures in cancer cell management.

Topics of interest for this Special Issue include, but are not limited to: non-viral vectors based on polymers, proteins, polysaccharides, liposomes, lipid nanoparticles, dendrimers, lipoplexes, polyplexes. It is our pleasure to invite you to submit a manuscript for this Special Issue. Full papers and reviews are all welcome.

Prof. Dr. Catalin Zaharia
Dr. Ionut-Cristian Radu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • polymers
  • polymeric nanoparticles
  • hydrogels
  • liposomes
  • lipid nanoparticles
  • polysaccharides
  • non-viral vector
  • cancer therapy
  • cancer gene therapy

Published Papers

There is no accepted submissions to this special issue at this moment.
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