Scaffold Materials for Bone Tissue Engineering
A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".
Deadline for manuscript submissions: 20 April 2026 | Viewed by 4
Special Issue Editor
Interests: materials science and engineering; tissue engineering; biomaterials; biomineralization; implants; biocompatible materials; functional materials; functional tissue and organs; biomechanics; bioelectronics; organ-on-chip; biosensors; polymer engineering; polymer physical chemistry; composites; 3D bioprinting; additive manufacturing; hydrogels; polymer chemistry; nanotechnology; spun fibers; knitted fabrics; scaffolds; biopolymers; ceramics; biodegradable materials; mechanical properties; X-ray scattering techniques, microstructural characterization; biomedical engineering
Special Issue Information
Dear Colleagues,
Innovative materials are used to design supports for bone, cartilage, subchondral bone tissue engineering (TE), and other biomedical applications. Polymer and composite materials, including those from natural resources, are extensively used to this end. Polymer biocompatibility, with desired bioactivity and low environmental risk, promises safe biomedical applications. Bone and bone–cartilage interface tissue engineering materials commonly present outstanding mechanical properties and fix to the target tissue region to ensure long-term support, repair, and possibly regeneration while providing adequate mechanical support.
Several works investigate the biological response and performance of bone TE biomaterials like hydrogels, scaffolds, membranes, films, foams, coatings, micro/nanoparticles, knitted fabrics, etc., in in vitro studies and preclinical and clinical applications. Advancement strategies focus on the development of bioinspired three-dimensional (3D) bioprinted constructs to fill irregularly shaped tissue defects, as well as on individualized medicine goals. There is increasing interest in using polymer/inorganic compound additive manufacturing to develop complex architectured 3D materials for bone tissue engineering. Generating functional biomaterial models that replicate the relevant aspects of bone tissue biomineralization, vascularization, and cell dynamic microenvironments in 3D is a major challenge. This may be addressed, for example, by combining 3D bioprinting and other biofabrication methods to biofabricate 3D hybrid organic/inorganic phase biomaterials, designed to approach in vitro the biological and physiological parameters of bone tissue as occurring in vivo, as recently addressed in on-chip platforms.
In this Special Issue, we welcome the inclusion of all types of materials used in bone and bone–cartilage interface tissue engineering and related biomedical applications. Special attention will be paid to researchers who (i) provide insight into the design and assessment of properties of the proposed materials; (ii) show the achievement of appropriate physical forms for target applications in relation to biology, biophysics, and biomedical engineering.
With kind regards,
Prof. Dr. Osorio Anayancy
Guest Editor
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Keywords
- tissue engineering
- polymer engineering
- nanoparticles
- hydrogels
- fibers
- ceramics
- biopolymers
- scaffolds
- 3D (bio)printing
- drug delivery
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