Marine Genomics and Metabolomics
A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Biotechnology Related to Drug Discovery or Production".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 975
Special Issue Editors
Interests: genomics; metabolomics; extremophilic bacteria; mass spectrometry; marine natural products
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Marine natural product (MNP) discovery strategies can be classified into two main categories, namely top-down and bottom-up approaches. Top-down approaches do not rely on previous knowledge of MNP biosynthetic gene clusters, and start with sample collection for microbial isolation or chemical extraction. Then, bioassay-guided fractionation and/or the metabolomic profiling of crude extracts lead to the isolation of bioactive hits for structural characterization. Bottom-up approaches mainly employ genome mining, functional genomics, and genetic engineering to elicit the production of MNPs, often encoded by cryptic genes.
Linking genomics and metabolomics has given new momentum to the identification of bioactive compounds from marine macro- and microorganisms. Therefore, this Special Issue invites articles on either genomic or metabolomic dereplication studies on marine macro- and microorganisms leading to the discovery and structural elucidation of novel secondary metabolites. We particularly welcome articles that integrate genomics and metabolomics to chart metabolic diversity in bacterial/fungal isolates as well as microbial communities.
Dr. Gerardo Della Sala
Dr. Fortunato Palma Esposito
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- marine microorganisms
- marine natural products
- metabolomics
- genomics
- heterologous expression
- genome mining
- biosynthetic gene clusters
- mass spectrometry
- molecular networking
- NMR
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