New Insights in Musculoskeletal Pathophysiology: From Space to Fish, and Beyond
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: closed (31 July 2021) | Viewed by 663
Special Issue Editor
Interests: clinical biochemistry; bone metastases; musculoskeletal ageing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Musculoskeletal disorders, mainly comprised of bone, muscle, tendon and joint diseases, represent one of the most common health problems worldwide with an enormous socioeconomic burden. During the last 20 years, new advances have been made in understanding the pathophysiology of the musculoskeletal system. As a result of these developments, novel pathogenetic pathways have been identified leading to the discovery of new molecular targets for therapeutic approaches. Innovative methodologies, such as microgravity conditions, mechanical loading experiments and 3D cellular models as well as novel biological approaches such as nutritional programming, chrono-biology, computational biology and utilisation of pioneering animal species, have led the way to elucidate the mechanisms of musculoskeletal diseases like sarcopenia, osteoporosis and osteoarthritis. In this Special Issue of the journal Life, we aim to collect articles that encompass the latest developments in musculoskeletal biology and provide a comprehensive update in the literature accessible to scientists from diverse fields. Thus, we wish to invite investigators from basic, clinical and translational musculoskeletal research or closely related disciplines to contribute with original research articles, but also with reviews and hypothesis-driven papers.
Dr. Ioannis Kanakis
Guest Editor
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Keywords
- bone biology
- muscle physiology
- musculoskeletal disorders
- microgravity
- mechanical loading
- circadian clocks
- bioinformatics
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