Laboratory Preparedness for Emerging Infectious Diseases

A special issue of Laboratories (ISSN 2813-8856).

Deadline for manuscript submissions: 30 April 2026 | Viewed by 418

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Animal Science Department, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288 GJ Rijswijk, The Netherlands
Interests: veterinary; infectious diseases; medicine
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Special Issue Information

Dear Colleagues,

Outbreaks of infectious diseases have had a profound and lasting effect on societies over the past decade, such as with SARS-CoV-2, avian influenza, Ebola virus, and currently monkey pox. Direct morbidity and mortality has occurred, but lasting effects like those of COVID-19 remain present. Often animal models for these emerging infectious diseases are urgently developed for studying the etiology, host immune mechanisms, and pathology of these diseases. Subsequently, the evaluation of the safety and efficacy of vaccines or drugs against these diseases are performed. This necessitates the ad hoc development of measures such as specific animal housing, barriers, waste disposal, effective methods of disinfection, and legislation.

This Special Issue will focus on all procedures, animals and employees, and laboratory preparedness for these outbreaks; topics include, but are not limited to, the following: laboratory animal housing, animal models, barriers, disinfection, and regulation and legislation.

We invite you to share your recent findings through this Special Issue.

Dr. Jaco Bakker
Guest Editor

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Keywords

  • laboratory animal housing
  • animal models
  • barriers
  • disinfection
  • regulation
  • legislation

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Published Papers (1 paper)

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Research

10 pages, 304 KB  
Article
Temporal Relationships Between Occupational Exposure to High Molecular Weight Allergens and Associated Short Latency Respiratory Health Outcomes: Laboratory Animal Allergens
by Howard Mason, Kate Jones and Laura Byrne
Laboratories 2025, 2(4), 19; https://doi.org/10.3390/laboratories2040019 - 29 Sep 2025
Abstract
Occupational asthma (OA) and rhinitis are health problems occurring in facilities employing animals for medical and scientific reasons. We have compared the UK trends (2006–2023) in these outcomes reported to the SWORD scheme with changes in routine and personal air monitoring for the [...] Read more.
Occupational asthma (OA) and rhinitis are health problems occurring in facilities employing animals for medical and scientific reasons. We have compared the UK trends (2006–2023) in these outcomes reported to the SWORD scheme with changes in routine and personal air monitoring for the major mouse (Mus m 1) and rat (Rat n 1) allergens. The exposure data contained 1540 and 688 mouse and rat results, respectively, expressed in ng.m−3. The median, 75th and 90th percentiles were used as exposure characteristics, and annually incrementing three-yearly rolling data slices compared exposure and health outcomes by linear regression. The median, P75 and P90 for Mus m 1 all showed annual declines of around 5–6% (p < 0.001), suggesting general improvements in controlling mouse allergen exposure, but without evidence of a decline in rat allergen levels (p > 0.05), although control measures for both species are largely identical. An annual mean decline in OA of 2.9% (p = 0.021) was identified, but without a significant decline in rhinitis (−1.4%; p = 0.21). Over 16 years, reductions in exposure to the predominant rodent species were accompanied by a concomitant but smaller reduction in OA. These data confirm the immediate value of controlling relevant allergen exposure in reducing the incidence of IgE-E mediated OA. Full article
(This article belongs to the Special Issue Laboratory Preparedness for Emerging Infectious Diseases)
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