Autoimmune Disease: Pathogenesis, Genetic Susceptibility and Novel Therapeutic Strategies
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Mechanisms of Diseases".
Deadline for manuscript submissions: closed (15 February 2024) | Viewed by 239
Special Issue Editor
Interests: rheumatic diseases; clinical rheumatology; autoimmunity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The purpose of this Special Issue, “Autoimmune Disease: Pathogenesis, Genetic Susceptibility and Novel Therapeutic Strategies”, aims to explore the new era of therapeutic strategies for the treatment of autoimmune diseases by discussing novel insights on pathogenesis of both common and rare systemic autoimmune diseases, mainly from the perspective of human genetics.
Autoimmune diseases are a group of disorders characterized by abnormal responses of B cells and T cells to the host. These intriguing disorders can occur widely and affect people of all ages, especially women from puberty. With the exception of an extremely small number of cases caused by single gene mutations, most autoimmune diseases result from the complex interplay between environmental and genetic factors. However, systemic autoimmune diseases are often diagnosed after overt symptoms appear, and treatment strategies are aimed at relieving symptoms rather than curing them. Therefore, timely and effective diagnostic strategies and treatment methods are needed. In recent years, due to the development of population genetics, evidence documents a deeper understanding of the genetic susceptibility to autoimmune diseases. This presents an opportunity for us to comprehensively re-examine autoimmunity-related genes and possible pathways.
This Special Issue aims to collect articles to increase the knowledge in the systemic autoimmune diseases area. In this Special Issue, original research articles and reviews are welcome. Mainly, we call for papers that are mainly focused on pathogenesis and genetic susceptibility of autoimmune diseases, both common and rare, along with new advances in its diagnosis and treatment.
Dr. Paola Triggianese
Guest Editor
Manuscript Submission Information
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Keywords
- autoimmunity
- biomarkers
- epigenetics
- genetics
- hormones
- pathogenesis
- personalized medicine
- proteomics
- rare diseases
- treat-to-target
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