Integrative Studies on Environmental Toxicity, Bioaccumulation and Remediation Strategies for Hazardous Substances, 2nd Edition

A special issue of Journal of Xenobiotics (ISSN 2039-4713).

Deadline for manuscript submissions: 25 July 2026 | Viewed by 1273

Special Issue Editors


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Guest Editor
1. Environmental Protection Agency (EPA), Washington, DC, USA
2. School of Veterinary Medicine, University of California, Davis, CA, USA
Interests: environmental toxicology; emerging contaminants; aquatic toxicology; pesticide chemistry and toxicology; human and ecological risk assessment
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Environmental toxicity and bioaccumulation represent critical areas of study regarding the pervasive impacts of toxic substances on both human health and ecological systems. This Special Issue of JOX delves into the multifaceted nature of toxic substance exposure, focusing on the pathways, mechanisms, and long-term effects of bioaccumulation in various environmental matrices.

This Special Issue will focus on the biomagnification of persistent organic pollutants (POPs), the dynamics of emerging contaminants, and the synergistic effects of complex chemical mixtures. Advanced analytical techniques, innovative risk assessment methodologies, and the development of robust regulatory frameworks will be featured. This Special Issue also aims to explore the intersection of environmental toxicity with public health, emphasizing the need for integrated approaches to mitigate adverse outcomes.

By assembling contributions from leading experts in toxicology, environmental science, and public health, this Special Issue seeks to enhance our understanding of the intricate interactions between toxic substances and biological systems. The insights provided by this Special Issue will be instrumental in developing effective environmental protection strategies and informing public health policies aimed at reducing the risk of exposure.

This Special Issue seeks to publish pioneering research on the intricate mechanisms, pathways, and long-term effects of exposure to toxic substances and their bioaccumulation.

The scope of this Special Issue includes, but is not limited to, the following topics:

  • Biomagnification and persistence of organic pollutants (POPs);
  • Dynamics and impact of emerging contaminants;
  • Synergistic effects of chemical mixtures;
  • Advanced analytical methodologies for toxicity assessment;
  • Innovative risk assessment and regulatory strategies;
  • Intersection of environmental toxicity and public health outcomes;
  • Innovative remediation strategies;
  • Microbial degradation of emerging contaminants.

The publications in the first edition, which we believe may be of interest to you, can be found here: https://www.mdpi.com/journal/jox/special_issues/31922JOSUK.

Dr. Mohamed A. Ghorab
Dr. Shaohua Chen
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Xenobiotics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomagnification and persistence of organic pollutants (POPs)
  • dynamics and impact of emerging contaminants
  • synergistic effects of chemical mixtures
  • advanced analytical methodologies for toxicity assessment
  • innovative risk assessment and regulatory strategies
  • intersection of environmental toxicity and public health outcomes
  • innovative remediation strategies
  • microbial degradation of emerging contaminants

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Published Papers (1 paper)

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Research

18 pages, 1025 KB  
Article
Simulation of the Impact of Pesticides on Pollinators Under Different Conditions Using Correlation Weighting of Quasi-SMILES Components Together with the Index of Ideality of Correlation (IIC)
by Alla P. Toropova, Andrey A. Toropov, Sofia Mescieri, Alessandra Roncaglioni and Emilio Benfenati
J. Xenobiot. 2026, 16(1), 10; https://doi.org/10.3390/jox16010010 - 8 Jan 2026
Viewed by 900
Abstract
Background: Pesticide toxicity to insects is an important adverse effect with a potentially large ecological impact when considering the effect on beneficial insects, as pollinators. The assessment of this endpoint is necessary to avoid applying ecologically dangerous pesticides. Aim of the study: [...] Read more.
Background: Pesticide toxicity to insects is an important adverse effect with a potentially large ecological impact when considering the effect on beneficial insects, as pollinators. The assessment of this endpoint is necessary to avoid applying ecologically dangerous pesticides. Aim of the study: Assessment of the availability of the Monte Carlo method for the development of a model for toxicity (pLD50) towards bees and other pollinators. In addition, the index of ideality of correlation is examined as a possibility to increase the statistical quality of quantitative structure–activity relationships (QSARs) for the toxicity of pesticides to pollinators. Main results and novelty: models with good performance on the toxic effect of pesticides towards different pollinators, wrapping acute and chronic effects, using the Monte Carlo method for QSAR analysis. Full article
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