Innovative Applications and Biomanufacturing of Fungi

A special issue of Journal of Fungi (ISSN 2309-608X).

Deadline for manuscript submissions: 30 June 2025 | Viewed by 6090

Special Issue Editor


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Guest Editor
Insititute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai 201403, China
Interests: fungi; lignocellulose degradation; enzymes; lignocellulosic conversion; fermentation; integrated pest management; plant protection; crop protection; plant pathology; fungal biology
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Special Issue Information

Dear Colleagues,

Fungi are among the most widespread and ecologically significant organisms on Earth, playing a crucial role as decomposers within various ecosystems. Fungi promote carbon and nitrogen cycling in the biosphere, and a variety of useful products are synthesized. Beyond their fundamental ecological functions, fungi are also remarkable for their capacity to synthesize a diverse array of useful products; some of these products are commercially produced, while others have innovative applications in green biomanufacturing.

This Special Issue will focus on the innovative applications and biomanufacturing of fungi, exploring cutting-edge biotechnology approaches for yeasts, molds, and mushrooms. This will include the innovative applications of fungi in industry, agriculture, medicine, and other fields. Studies on the genetic mechanisms of the abovementioned aspects are welcome.

Prof. Dr. Gen Zou
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Fungi is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biotechnology
  • biomolecule
  • Innovative application
  • genetic mechanism

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Published Papers (2 papers)

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Research

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17 pages, 4567 KiB  
Article
Enhancing Digestibility and Intestinal Peptide Release of Pleurotus eryngii Protein: An Enzymatic Approach
by Dandan Wang, Meng Zhang, Jianing Wan, Haiquan Liu, Ying Wang, Ruiheng Yang, Yingying Wu, Dapeng Bao, Hongyu Chen, Gen Zou and Yong Zhao
J. Fungi 2024, 10(12), 890; https://doi.org/10.3390/jof10120890 - 23 Dec 2024
Viewed by 846
Abstract
Pleurotus eryngii is a tasty and low-calorie mushroom containing abundant high-quality protein. This study aims to improve the digestibility of P. eryngii protein (PEP) and hence to facilitate its development as a healthy alternative protein. The extracted PEP was pretreated with 1000–5000 U [...] Read more.
Pleurotus eryngii is a tasty and low-calorie mushroom containing abundant high-quality protein. This study aims to improve the digestibility of P. eryngii protein (PEP) and hence to facilitate its development as a healthy alternative protein. The extracted PEP was pretreated with 1000–5000 U of papain, neutral protease and alkaline protease. The Chyme collected from in vitro simulated gastrointestinal digestion was analyzed by fluorescence microscopy and protein particle analyzer, and the endpoint profiles of peptides and amino acids were determined by UHPLC-MS/MS and NanoLC-MS/MS. The particle size curve and fluorescence microscopy images jointly supported that protease hydrolysis improved decomposition and dispersion of PEP during digestion, particularly in the gastric phase. The impact on Zeta potential was minimal. Proteases effectively increased the abundance of amino acids after digestion, particularly L-isomer Lys and Arg Maximum release was achieved when pretreated with 5000 U of alkaline protease, reaching 7.54 times that of control. Pretreatments by proteases also notably increased digestive yields of 16,736–19,870 peptides, with the maximum reaching 1.70 times that of the control, which mainly consisted of small peptides composed of 7–15 amino acids with molecular weight below 800 Da. The findings indicated that protease hydrolysis, especially pretreatment with 5000 U of alkaline protease, effectively enhanced the digestibility of PEP, which shed light on providing enzymatic approaches for improving bioavailability and developing healthy fungal proteins. Full article
(This article belongs to the Special Issue Innovative Applications and Biomanufacturing of Fungi)
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Review

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19 pages, 876 KiB  
Review
Advanced Fungal Biotechnologies in Accomplishing Sustainable Development Goals (SDGs): What Do We Know and What Comes Next?
by Pragya Tiwari and Kyeung-Il Park
J. Fungi 2024, 10(7), 506; https://doi.org/10.3390/jof10070506 - 22 Jul 2024
Cited by 4 | Viewed by 4674
Abstract
The present era has witnessed an unprecedented scenario with extreme climate changes, depleting natural resources and rising global food demands and its widespread societal impact. From providing bio-based resources to fulfilling socio-economic necessities, tackling environmental challenges, and ecosystem restoration, microbes exist as integral [...] Read more.
The present era has witnessed an unprecedented scenario with extreme climate changes, depleting natural resources and rising global food demands and its widespread societal impact. From providing bio-based resources to fulfilling socio-economic necessities, tackling environmental challenges, and ecosystem restoration, microbes exist as integral members of the ecosystem and influence human lives. Microbes demonstrate remarkable potential to adapt and thrive in climatic variations and extreme niches and promote environmental sustainability. It is important to mention that advances in fungal biotechnologies have opened new avenues and significantly contributed to improving human lives through addressing socio-economic challenges. Microbe-based sustainable innovations would likely contribute to the United Nations sustainable development goals (SDGs) by providing affordable energy (use of agro-industrial waste by microbial conversions), reducing economic burdens/affordable living conditions (new opportunities by the creation of bio-based industries for a sustainable living), tackling climatic changes (use of sustainable alternative fuels for reducing carbon footprints), conserving marine life (production of microbe-based bioplastics for safer marine life) and poverty reduction (microbial products), among other microbe-mediated approaches. The article highlights the emerging trends and future directions into how fungal biotechnologies can provide feasible and sustainable solutions to achieve SDGs and address global issues. Full article
(This article belongs to the Special Issue Innovative Applications and Biomanufacturing of Fungi)
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