Diagnostic Imaging: From Basic Knowledge to Latest Advancements

A special issue of Journal of Imaging (ISSN 2313-433X). This special issue belongs to the section "Medical Imaging".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 1462

Special Issue Editor

Special Issue Information

Dear Colleagues,

Since its birth in 1895, Diagnostic Imaging has undergone significant transformation and continues to evolve due to ongoing advancements in medical knowledge and technological equipment. The first major advancement in radiology was cross-sectional imaging, and today’s quantitative imaging technologies are enhancing the significance and clinical precision of diagnostic radiology.

In addition, advances in diagnostic imaging aid in the precise guidance of interventional procedures, from biopsies to other selected treatments.

This Special Issue aims to present a collection of high-quality articles that address all types of imaging. We aim to provide a deeper understanding of both recent advances in the field and fundamental information.

The scope of this Special Issue includes, but is not limited to, the following topics:

  • Advancements in MRI and CT applications;
  • Conventional Radiography;
  • Oncologic Imaging;
  • Musculoskeletal Imaging;
  • Imaging of rare diseases.

Dr. Paolo Spinnato
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Imaging is an international peer-reviewed open access monthly journal published by MDPI.

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Keywords

  • magnetic resonance imaging
  • computed tomography
  • sarcoma
  • interventional radiology
  • bone and bones

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Published Papers (1 paper)

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Review

16 pages, 601 KB  
Review
The Retina as a Proxy for Brain Neurodegeneration: A Narrative Review on OCT-Based Retinal Imaging in the Early Detection of Alzheimer’s and Parkinson’s Disease
by Ouafa Sijilmassi
J. Imaging 2026, 12(3), 104; https://doi.org/10.3390/jimaging12030104 - 27 Feb 2026
Viewed by 1165
Abstract
Neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD), are major causes of cognitive and motor decline, yet early diagnosis remains challenging due to asymptomatic phases and limited non-invasive biomarkers. This narrative review systematically synthesized studies on retinal imaging in AD and [...] Read more.
Neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD), are major causes of cognitive and motor decline, yet early diagnosis remains challenging due to asymptomatic phases and limited non-invasive biomarkers. This narrative review systematically synthesized studies on retinal imaging in AD and PD. Published studies were identified through searches of PubMed, MEDLINE, Google Scholar, and reference lists, focusing on Optical Coherence Tomography (OCT), OCT Angiography (OCTA), and Spectral-Domain OCT (SD-OCT) assessing retinal structural and vascular changes. Data were extracted on retinal layer thickness, vascular parameters, and diagnostic metrics. Findings indicate that both diseases consistently exhibit thinning of inner retinal layers, particularly the retinal nerve fiber layer (RNFL) and ganglion cell–inner plexiform layer (GCIPL). In AD, studies reported progressive inner retinal thinning across disease stages, sometimes accompanied by outer retinal and retinal pigment epithelium changes. In PD, thinning was observed predominantly in RNFL and GCIPL, correlating with disease duration and motor severity. Microvascular alterations were described in both disorders, with disease-specific spatial patterns reported across studies. Overall, retinal imaging emerges as a non-invasive, high-resolution, and cost-effective tool for early detection, differential assessment, and longitudinal monitoring of neurodegenerative diseases. These findings support the translation of retinal biomarkers into clinical practice for improved disease management. Full article
(This article belongs to the Special Issue Diagnostic Imaging: From Basic Knowledge to Latest Advancements)
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