Innovative Physiotherapy Approaches and Functional Outcomes in Neurological and Developmental Disorders

A special issue of Journal of Functional Morphology and Kinesiology (ISSN 2411-5142). This special issue belongs to the section "Kinesiology and Biomechanics".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 2098

Special Issue Editors


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Guest Editor
Physiotherapy Department, School of Health and Care Sciences, University of West Attica, Agiou Spidonos 28, 2243 Athens, Greece
Interests: physiotherapy; human balance; gait analysis; neurological rehabilitation; ergonomics; fall prevention; motor control; geriatrics; sensorimotor integration; clinical education in physiotherapy
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Guest Editor
Centre for Human & Applied Physiological Sciences, King’s College, London WC2R 2LS, UK
Interests: physiotherapy; human balance; gait analysis; neurological rehabilitation; falls prevention, assessment and rehabilitation; motor control; older adults; sensorimotor integration; advances in technology for neurological rehabilitation

Special Issue Information

Dear Colleagues,

This Special Issue, titled “Innovative Physiotherapy Approaches and Functional Outcomes in Neurological and Developmental Disorders”, aims at presenting cutting-edge research and clinical advances that enhance functional outcomes, quality of life, and independence in individuals with neurological and developmental conditions. We welcome original research articles, systematic reviews, and high-quality case studies focusing on novel physiotherapy interventions, evidence-based therapeutic techniques, and integrated rehabilitation strategies. Topics of interest include, but are not limited to, human balance, gait analysis, motor control, sensorimotor integration, and fall prevention, as well as the application of assistive technologies, robotics, and virtual reality in rehabilitation. Contributions exploring ergonomics, task-specific training, and multidisciplinary approaches across the lifespan are also encouraged. By fostering dialogue between researchers, clinicians, and educators, this Special Issue seeks to advance knowledge, promote innovation, and support the translation of research into practice for improved patient outcomes in neurological and developmental rehabilitation.

Prof. Dr. Vasiliki Sakellari
Dr. Marousa Pavlou
Guest Editors

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Keywords

  • physiotherapy
  • neurological rehabilitation
  • evidence-based practice
  • developmental disorders
  • motor control
  • balance
  • gait
  • assistive technology
  • virtual reality
  • robotics

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Published Papers (3 papers)

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Research

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19 pages, 1655 KB  
Article
Neurofunctional Assessments in Lumbar Spondylosis: Outcomes After Rehabilitation Treatment
by Andreea Ancuta Talinga, Roxana Ramona Onofrei, Ada-Maria Codreanu, Alexandra Laura Mederle, Veronica Aurelia Romanescu, Marius-Zoltan Rezumes, Oana Suciu, Dan-Andrei Korodi and Claudia Borza
J. Funct. Morphol. Kinesiol. 2026, 11(1), 114; https://doi.org/10.3390/jfmk11010114 - 9 Mar 2026
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Abstract
Background: Lumbar spondylosis is a frequent cause of chronic low back pain, often associated with radiculopathy. Although imaging evaluation is widely used, it does not always reflect the degree of functional impairment of the nerve roots. Electrophysiological assessments, such as nerve conduction [...] Read more.
Background: Lumbar spondylosis is a frequent cause of chronic low back pain, often associated with radiculopathy. Although imaging evaluation is widely used, it does not always reflect the degree of functional impairment of the nerve roots. Electrophysiological assessments, such as nerve conduction studies (NCS) and surface electromyography (sEMG), can provide additional information on neuromuscular function under conservative treatment. Methods: This quasi-experimental study included 60 patients with lumbar spondylosis and 25 healthy subjects, who underwent clinical, imaging, and electrophysiological assessments. NCS and sEMG parameters were assessed in the patient group before and six months after rehabilitation treatment. The control group was assessed only once, at baseline. We analyzed the nerve conduction velocity of the tibial and peroneal nerves and the sEMG activity of the tibialis anterior muscle bilaterally. Statistical analysis used nonparametric tests, Spearman’s coefficient, and Hodges–Lehmann estimates. Results: Compared to the control group, patients presented increased residual latencies and reduced CMAP amplitude and motor conduction velocity values (p < 0.001). After rehabilitation treatment, significant improvements in NCS parameters were observed, with decreased latencies and increased CMAP amplitude and motor conduction velocity bilaterally (p < 0.001). Also, sEMG amplitude and recruitment pattern scores increased significantly at the 6-month follow-up (p ≤ 0.004). Correlations between electrophysiological parameters and the severity of imaging changes were limited, with modest associations for left tibial latencies (ρ = 0.401–0.467; p < 0.050). Conclusions: In patients with lumbar spondylosis, rehabilitation treatment was associated with functional improvements in nerve conduction velocity parameters and muscle activity. Full article
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Review

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27 pages, 666 KB  
Review
Progressive Resistance Training in Parkinson’s Disease: An Umbrella Review Examining the Role of Methodological Adherence and Training Progression Principles in Clinical Outcome
by Ya’ara Rozenbaum, Yeshayahu Hutzler and Sharon Barak
J. Funct. Morphol. Kinesiol. 2026, 11(2), 178; https://doi.org/10.3390/jfmk11020178 - 28 Apr 2026
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Abstract
Objective: The goal was to investigate the relationship between methodological adherence and clinical outcomes in Progressive Resistance Training (PRT) for Parkinson’s Disease (PD), specifically identifying why findings of “superiority” over active controls remain inconsistent. Methods: This umbrella review utilized a multi-stage process to [...] Read more.
Objective: The goal was to investigate the relationship between methodological adherence and clinical outcomes in Progressive Resistance Training (PRT) for Parkinson’s Disease (PD), specifically identifying why findings of “superiority” over active controls remain inconsistent. Methods: This umbrella review utilized a multi-stage process to identify a sample of the primary literature for methodological analysis. An initial search identified 38 systematic reviews published within the specified timeframe. From the reference lists of these reviews, a subset of 34 primary clinical studies was purposefully selected. Inclusion was prioritized for studies providing comprehensive methodological data on PRT protocols and standardized clinical outcomes. Interventions were evaluated using a three-tiered framework: (1) training protocol with specifications of Frequency, Intensity, Time, Type, Volume, and Progression (FITT-VP) (General Exercise), (2) FITT-VP integrated with the American College of Sports Medicine (ACSM) Supplementary Guidelines (Integrated Guidelines), and (3) principles of progression (mechanistic growth). Studies were categorized by control type (active (e.g., aerobic or balance), n = 26; passive (e.g., standard care or no exercise), n = 8). Results: In trials that compared PRT with an active control group, PRT achieved clinical superiority in 57% (n = 15) of trials and 46% (n = 12) when focusing on trials with an effect on specific functional or balance outcomes. Among these successful interventions, 75% maintained high adherence (≥70%) to the Integrated Guidelines, and 58% maintained high adherence to the principles of progression. In the 53% (n = 14) of studies where PRT was found non-superior (equivalent or inferior in functional or balance outcomes) to an active control, 0% met the high adherence threshold for progression. While general FITT-VP compliance remained high (78%), the failure to implement systematic load, specificity, and variation served as a definitive barrier to competitive superiority. In the 100% of studies where PRT outperformed passive controls, high progression was present in 57% of cases. This may suggest that while a baseline resistance stimulus outperforms inactivity, it is fundamentally insufficient to outperform other active clinical therapies. Conclusions: This umbrella review indicates that adherence to the principles of progression may be an important factor influencing the clinical outcomes of PRT in individuals with PD. The variability observed in the current literature suggests that inconsistent application of established exercise frameworks—rather than the failure of the modality itself—could be a contributing element to the reported “inconclusiveness.” To potentially enhance functional outcomes and the comparative effectiveness of PRT, future research should consider prioritizing structured adherence to FITT-VP, Integrated Guidelines, and progression-based frameworks. Establishing a 70% adherence threshold is proposed as a potential benchmark to improve protocol consistency and support rehabilitation efficacy in this population. Full article
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Other

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8 pages, 1354 KB  
Case Report
Morphological and Motor Ability Adaptations Following a Short-Term Moderate-Intensity Strength Training Intervention in a Sedentary Adult Male with Asymmetrical Bilateral Spastic Cerebral Palsy: A Case Study
by Aleksandra Popović, Marko Kapeleti, Igor Zlatović, Milica Jankucić, Anastasija Kocić, Vladimir Mrdaković and Marija Macura
J. Funct. Morphol. Kinesiol. 2025, 10(4), 442; https://doi.org/10.3390/jfmk10040442 - 17 Nov 2025
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Abstract
Background: Cerebral palsy (CP) is a group of permanent disorders affecting movement, posture, and balance. Spasticity is the most common movement disorder in CP, and muscle weakness is its primary impairment. There is a lack of studies that have examined the effects [...] Read more.
Background: Cerebral palsy (CP) is a group of permanent disorders affecting movement, posture, and balance. Spasticity is the most common movement disorder in CP, and muscle weakness is its primary impairment. There is a lack of studies that have examined the effects of short-term, moderate-intensity strength training (ST) in adults with CP, whereas recommendations suggest that long-term interventions are necessary for substantial improvements in strength in the CP population. This study investigated the effects of a 5-week, moderate-intensity ST intervention, that targets various upper and lower extremity muscles, on multiple morphological characteristics (MC) and motor abilities (MA) in a sedentary 30-year-old adult male with asymmetrical bilateral spastic CP level II. Methods: Body composition, maximal knee strength, maximal squat strength, leg explosive strength, and hip mobility were assessed before and after the ST intervention. Results: Changes in body composition were modest (0.6–6.4%). Maximal knee strength increased moderately on the less spastic side (40.7–65.9%) and substantially on the more spastic side (118.5–130.6%). Hip mobility showed a similar pattern, with small to moderate improvements (11.4–30.0%), while maximal squat strength and leg explosive strength increased moderately (29.5–46.3%). Conclusions: A short-term, moderate-intensity ST intervention produced meaningful improvements in MC and MA in this subject, especially on the more spastic side. The applied ST program was feasible and potentially efficient, and the results of this single-case study support its approach and methodology in necessary future studies on larger trials in an attempt to generalize these preliminary findings. This in turn may encourage practitioners to promote increased participation in physical activity among individuals with CP, given the short-term period of adaptations. The study discusses the potential of further refinement of the existing CP-specific ST guidelines and load programming aspects. Full article
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