Valve Metal and Valve Metal-Oxide-Based Materials for Biomedical Applications

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Synthesis of Biomaterials via Advanced Technologies".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 1064

Special Issue Editors


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Guest Editor
Chemistry and Structure of Novel Materials, University of Siegen, Paul-Bonatz-Str. 9-11, 57076 Siegen, Germany
Interests: functional materials; drug-delivery; nanostructures; nanomaterials; implants; surface modifications; biomechanics; organic molecules; coatings; vesicles

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Guest Editor
Department of Otorhinolaryngology Head and Neck Surgery, Bio-Mechanics & Materials Group, University Medical Center, Johannes Gutenberg-University Mainz, 55131 Mainz, Germany
Interests: bone implants; dental implants; bone healing; finite element method; 3D printing; composites; biomechanics; surface functionalization
School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
Interests: nanoparticle-tissue/cell interaction; nanoparticle-based photodynamic therapy; disinfection by nanomaterials

Special Issue Information

Dear Colleagues,

This Special Issue aims to compile groundbreaking work on valve metal-oxide nanomaterials in the biomedical field. With their remarkable biocompatibility, mechanical strength, and chemical stability, these materials are at the forefront of revolutionizing tissue engineering, cancer treatments, biosensing technologies, and even implants and implant surfaces. We welcome original research articles and comprehensive reviews that focus on valve metal-oxide nanomaterials for biomedical applications.

Dr. Swathi Naidu Vakamulla Raghu
Dr. Gargi Shankar Nayak
Dr. Ke Tao
Guest Editors

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Keywords

  • nanostructures
  • nanomaterials
  • biomineralization
  • ceramic
  • implants
  • healthcare

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Published Papers (1 paper)

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Research

24 pages, 4170 KB  
Article
Surface-Activated Zirconia Nanotubes with UV-Assisted Mg Deposition: Novel Bioinstructive Implants
by Swathi N. V. Raghu, Yomna Badran, Shanmugapriya Periyannan and Manuela S. Killian
J. Funct. Biomater. 2026, 17(3), 158; https://doi.org/10.3390/jfb17030158 - 23 Mar 2026
Viewed by 596
Abstract
Modern bioimplants increasingly depend on surface-engineered functionality to elicit adaptive biological responses. One promising strategy involves the electrodeposition of bioresponsive elements such as magnesium (Mg), which plays a critical role in osseointegration. In this study, we present a novel approach for modifying anodized [...] Read more.
Modern bioimplants increasingly depend on surface-engineered functionality to elicit adaptive biological responses. One promising strategy involves the electrodeposition of bioresponsive elements such as magnesium (Mg), which plays a critical role in osseointegration. In this study, we present a novel approach for modifying anodized zirconia nanotubes (ZrNTs) via Mg decoration using electrochemical deposition. A controlled pulsed cathodic linear sweep protocol was employed to control Mg deposition behaviour, enabling reduced clustering and improved spatial distribution. Notably, ultraviolet (UV) irradiation was found to influence Mg adsorption dynamics, revealing a distinct pattern of interaction. Comprehensive surface characterization was conducted to assess nanotube morphology, Mg adherence, and distribution. These modified surfaces were subsequently evaluated for their potential in further functionalization, targeting surface chemistries conducive to biomaterial viability. The biomineralization capacity of Mg-decorated ZrNTs was systematically investigated using electrochemical impedance spectroscopy (EIS) and Tafel analysis, demonstrating enhanced apatite formation and improved corrosion resistance. This work establishes Mg decoration of ZrNTs as a viable route for developing bioactive, corrosion-resistant implant surfaces. Full article
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