Advancements in Biomaterials for Bone Tissue Engineering
A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Bone Biomaterials".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 178
Special Issue Editors
2. Biodesign Europe, Dublin City University, Dublin, Ireland
Interests: biomedical materials; tissue engineering; bone scaffolds; preclinical research; regenerative medicine
Special Issue Information
Dear Colleagues,
Bone defect repair remains a significant clinical challenge. While current treatments such as autografts and allografts are commonly employed, they are associated with limitations, including donor site morbidity, limited availability, and risk of immune response or disease transmission. To address these concerns, synthetic biomaterial-based bone grafts and tissue-engineered scaffolds have emerged as promising alternatives. These bone scaffolds provide a structural framework that supports cellular attachment, proliferation, and the formation of new tissue, aiming to replicate the complex architecture and osteogenic functionality of native bone.
Despite remarkable progress in this field, developing scaffolds that meet the required mechanical strength, bioactivity, biodegradability, and interconnected porosity remains challenging. As research evolves, new materials and fabrication techniques, including 3D printing, biofabrication, and surface modification, are being explored to improve scaffold performance and clinical outcomes.
This Special Issue on "Advancements in Biomaterials for Bone Tissue Engineering" focuses on recent breakthroughs at the intersection of biomaterials science, tissue engineering, and regenerative medicine. We aim to highlight innovative materials and strategies that enhance bone regeneration and better mimic the native bone microenvironment.
We invite original research articles and comprehensive reviews addressing, but not limited to, the following topics:
- Novel biomaterials for bone scaffold development;
- Bone–scaffold cellular interactions and osteogenesis;
- 3D printing and bioprinting technologies for scaffold fabrication;
- Preclinical studies and translational research in bone tissue engineering;
- Surface modification and functionalization of scaffolds;
- Controlled release systems for growth factors and bioactives;
- Mechanical behaviour and degradation kinetics of scaffolds.
We look forward to your valuable contributions that will help drive forward the next generation of bone tissue engineering solutions.
Dr. MohammadAli Sahebalzamani
Prof. Dr. Xiaodu Wang
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bone tissue engineering
- bone scaffolds
- biomaterials
- 3D printing
- osteoconductive scaffolds
- biodegradable polymers
- mesenchymal stem cells
- bioactive coating
- bone regeneration
- translational research
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