Recent Advances in Biomaterials for Tissue Regeneration and Functional Restoration

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials for Tissue Engineering and Regenerative Medicine".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 15

Special Issue Editor

Department of Biomedical Engineering, School of Engineering, Tufts University Science & Technology Center, Medford, MA 02155, USA
Interests: tissue engineering; regenerative biomaterials; cell nano-coating technologies; functional scaffold systems; human-relevant 3D tissue models to enable tissue regeneration; functional restoration; biomaterial-guided regulation of cell–tissue interactions

Special Issue Information

Dear Colleagues,

Biomaterials have evolved far beyond passive replacement materials. Today, they are increasingly designed to actively engage biology, guiding cell behavior, shaping tissue microenvironments, and ultimately determining whether regeneration leads to meaningful functional restoration. This Special Issue, Recent Advances in Biomaterials for Tissue Regeneration Applications and Functional Restoration, highlights work that deliberately links materials design to biological mechanism and functional performance, with a clear eye toward translational impact.

We welcome contributions covering natural and synthetic biomaterials, hybrid and composite systems, micro- and nano-engineered surfaces, and emerging strategies such as cell surface nano-coatings, dynamic and stimuli-responsive (“smart”) materials, and advanced biofabrication approaches. A key challenge—and opportunity—in the field is to move beyond passive scaffolding and develop materials that actively coordinate host responses, including immune modulation, while supporting vascular, neural, and multicellular integration within regenerating tissues.

Equally important is the growing need for reproducible, well-defined material platforms that enable human-relevant tissue models, including organoids and engineered tissues, and reduce the reliance on poorly defined or highly variable substrates. Finally, this Special Issue encourages work that considers manufacturability, scalability, and real-world constraints, recognizing that successful regenerative biomaterials must be not only innovative, but also robust and deployable.

Dr. Ying Chen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • tissue regeneration
  • functional restoration
  • tissue engineering
  • cell–material interactions
  • translational biomaterials

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Published Papers

This special issue is now open for submission.
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