Molecular and Cellular Mechanisms of Brain Development and Neurodevelopmental Disorders
A special issue of Journal of Developmental Biology (ISSN 2221-3759).
Deadline for manuscript submissions: closed (30 November 2025) | Viewed by 1159
Special Issue Editor
Interests: epigenetics; DNA methylation; transcriptional control; gene regulation; drug repurposing; neural stem cells; neurodevelopmental disorders; medulloblastoma brain tumor
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Brain development is a complex process that is highly regulated at different cellular and molecular levels. Accordingly, specific regulatory mechanisms are in place to ensure the proper expression of key developmental genes. During development, a population of neuronal progenitor cells known as neural stem cells build the central nervous system through differentiating into specific cell types. These progenitor cells represent fundamental biological systems that can be used to study the mechanisms of cell fate determination in the developing and adult brain. Such systems could include in vitro and in vivo models, benefiting from classical and novel technologies.
This Special Issue welcomes review articles and original research studies that cover relevant research in model systems that investigate different molecular and cellular mechanisms of brain development and their impact in neurodevelopmental disorders. We encourage submissions in different areas of research and disciplines, including embryonic brain development and adult brain function and physiology, the epigenetic basis of brain cell development and their deregulation in neurodevelopmental diseases, cell signaling pathways in brain cells, neural stem cell differentiation and self-renewal, gene regulatory mechanisms in relevant model systems, the molecular and cellular basis of brain diseases, next-generation sequencing and multi-omics studies, and neuroscience.
You may choose our Joint Special Issue in Cells.
Prof. Dr. Mojgan Rastegar
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Developmental Biology is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- brain development
- neural stem cells
- neurodevelopmental disorders
- brain diseases
- cellular and molecular mechanisms
- embryonic and adult brain
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