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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Advances in Hearing Loss: Diagnosis, Treatment, and Management
edited by
submission deadline 20 Aug 2026 | Viewed by 33 | Submission Open
Keywords: hearing loss; deafness; bone conduction implants; middle ear implants; cochlear implants; myringoplasty; tympanoplasty; stapedotomy; ossicular chain reconstruction; imaging; audiological diagnostic
(This special issue belongs to the Section Otolaryngology)
Therapeutic Advances and Emerging Treatments in Inflammatory Bowel Disease
edited by
submission deadline 20 Aug 2026 | Viewed by 32 | Submission Open
Keywords: inflammatory bowel disease; therapeutic advances emerging treatments; biologics and small molecules; precision medicine in IBD; pharmacokinetic model
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Contemporary Coronary Intervention: Innovation, Evidence, and Patient-Centred Outcomes
edited by Kevin Liou
submission deadline 20 Aug 2026 | Viewed by 31 | Submission Open
Keywords: percutaneous coronary interventions; coronary imaging; coronary physiology; precision medicine; CHIP PCI; stent-less technologies; clinical outcomes; pharmacotherapy in PCI; biomarkers; artificial intelligence in PCI; sustainability in PCI
(This special issue belongs to the Section Cardiology)
Clinics and Management of Allergic and Inflammatory Skin Disorders submission deadline 20 Aug 2026 | Viewed by 28 | Submission Open
Keywords: allergic dermatoses; chronic inflammatory dermatoses; atopic dermatosis; contact dermatitis; chronic urticria; rosacea; psoriasis; hidradenitis suppurativa; diagnosis; comorbidities; management
(This special issue belongs to the Section Dermatology)
Clinical Perspectives on Extracorporeal Membrane Oxygenation (ECMO)
edited by
submission deadline 20 Aug 2026 | Viewed by 28 | Submission Open
Keywords: extracorporeal membrane oxygenation (ECMO); extracorporeal life support (ECLS); extracorporeal cardiopulmonary resuscitation (eCPR); extracorporeal gas exchange; extracorporeal circulation; acute respiratory distress syndrome (ARDS); cardiogenic shock (CS)
(This special issue belongs to the Section Intensive Care)
Endocrine Surgery: Current Treatment and Future Options
edited by Pietro Princi and
submission deadline 20 Aug 2026 | Viewed by 27 | Submission Open
Keywords: endocrine surgery; thyroid surgery; parathyroid surgery; adrenal gland surgery; neuroendocrine neoplasms; thyroid cancer; thyroid cancer treatment; surgical endocrinology; robotic endocrine surgery; laparoscopic adrenalectomy; ret-roperitoneoscopic adrenalectomy; parathyroidectomy; benign thyroid disease; thyroid ablation
(This special issue belongs to the Section General Surgery)
Targeting Extravalvular Burden Associated with Valvular Heart Disease
edited by
submission deadline 20 Aug 2026 | Viewed by 26 | Submission Open
Keywords: valvular heart disease; systemic disorder; extravalvular burden; valve dysfunction; valve intervention; multimodality imaging
(This special issue belongs to the Section Cardiology)
Endometriosis: Advances in Diagnosis, Treatment, and Long-Term Outcomes
edited by
submission deadline 20 Aug 2026 | Viewed by 26 | Submission Open
Keywords: endometriosis; diagnosis and biomarkers; medical and surgical treatment; fertility and reproductive outcomes; pain management; quality of life; long-term follow-up
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Diagnosis, Monitoring, and Treatment of Myocardial Infarction
edited by
submission deadline 20 Aug 2026 | Viewed by 26 | Submission Open
Keywords: myocardial infarction (MI); occlusion myocardial infarction (OMI); myocardial infarction with non-obstructive coronary arteries (MINOCA); diagnosis; monitoring; treatment
(This special issue belongs to the Section Cardiovascular Medicine)
Anesthesia and Intensive Care: Clinical Practices and Prospects
edited by
submission deadline 20 Aug 2026 | Viewed by 25 | Submission Open
Keywords: artificial intelligence; clinical decision support; perioperative risk stratification; perioperative patient safety; hemodynamic optimization
(This special issue belongs to the Section Intensive Care)
Pharmacological Pain Management Advances
edited by Michael A. Ueberall
submission deadline 20 Aug 2026 | Viewed by 25 | Submission Open
Keywords: pain management; drug therapy; analgesics; co-analgesics; drug safety and drug interactions; real-world evidence
(This special issue belongs to the Section Anesthesiology)
Current Concepts and Technological Innovations in Hepato-Pancreato-Biliary Surgery and Transplantation
edited by Michele Finotti and Francesco D’Amico
submission deadline 20 Aug 2026 | Viewed by 25 | Submission Open
Keywords: hepato-pancreato-biliary surgery; hepato-pancreato-biliary transplantation; pancreatic cancer; hepatobiliary cancer; vascular reconstruction; minimally invasive in hepato-pancreato-biliary surgery; robotic techniques; organ-preservation strategies
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Optimizing Blood Management in Perioperative Cardiac Care: A Multidisciplinary Approach
edited by
submission deadline 20 Aug 2026 | Viewed by 24 | Submission Open
Keywords: perioperative cardiac care; patient blood management; cardiac surgery; blood transfusion; transfusion thresholds; bleeding management; hemostatic therapy; anticoagulation management; point‑of‑care coagulation testing
(This special issue belongs to the Section Cardiology)
Revisional and Conversion Bariatric Surgery: Safety and Outcomes
edited by Jerry Dang
submission deadline 20 Aug 2026 | Viewed by 23 | Submission Open
Keywords: revisional bariatric surgery; conversion surgery; weight recurrence; surgical outcomes; sleeve gastrectomy; roux-en-y gastric bypass; post-bariatric complications; GERD
(This special issue belongs to the Section General Surgery)
Advances in Trauma and Orthopedic Surgery: 3rd Edition submission deadline 20 Aug 2026 | Viewed by 21 | Submission Open
Keywords: trauma; fracture; fracture fixation; osteosynthesis; biomechanics; bone; approach; nonunion; joint replacement; outcome
(This special issue belongs to the Section Orthopedics)
Advances in Pulmonary Embolism Therapeutic
edited by
submission deadline 20 Aug 2026 | Viewed by 19 | Submission Open
Keywords: acute pulmonary embolism; chronic pulmonary embolism; chronic thromboembolic disease; chronic thromboem-bolic pulmonary hypertension; catheter-directed therapy; pulmonary endarterectomy; balloon pulmonary angio-plasty
(This special issue belongs to the Section Vascular Medicine)
Updates on Neuromuscular Diseases
edited by
submission deadline 20 Aug 2026 | Viewed by 19 | Submission Open
Keywords: neuromuscualr disorders; myopathies; neuropathies; neuromuscualr junction disorders; neurogenetics
(This special issue belongs to the Section Clinical Neurology)
Clinical Applications and Surgical Integration of Advanced Ophthalmic Imaging
edited by Katarzyna Nowomiejska
submission deadline 20 Aug 2026 | Viewed by 14 | Submission Open
Keywords: ophthalmic imaging; retina; intraoperative OCT; personalized treatment; clinical applications
(This special issue belongs to the Section Ophthalmology)
Managing Chronic Kidney Disease: Current Practices and Future Perspectives
edited by Maria L. Gonzalez-Suarez
submission deadline 20 Aug 2026 | Viewed by 12 | Submission Open
Keywords: chronic kidney disease; diabetic kidney disease; kidney failure; guideline-directed therapies; SLGT 2 inhibitors; GLP1 receptor agonists
(This special issue belongs to the Section Nephrology & Urology)
Cardiovascular Prevention and Epidemiology: Innovations and Insights Bridging Research and Practice for Effective Risk Reduction
edited by and Maria Maiello
submission deadline 20 Aug 2026 | Viewed by 12 | Submission Open
Keywords: cardiovascular prevention; risk reduction; epidemiology; innovations; risk stratification; population health
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Advances in Adult Deformities and Spinal Disorders: Surgical Treatment and Pre- and Post-Operative Re-Habilitation
edited by Laura Scaramuzzo
submission deadline 20 Aug 2026 | Viewed by 11 | Submission Open
Keywords: scoliosis; spine; kyphosis; degenerative spine; spine surgery
(This special issue belongs to the Section Orthopedics)
Future-Proof Care for Patients with Kidney Stones
edited by and Oliver Wiseman
submission deadline 20 Aug 2026 | Viewed by 10 | Submission Open
Keywords: effectiveness; resilience; prevention; care pathways; urolithiasis; kidney stones; PCNL; URS; ESWL; quality of life
(This special issue belongs to the Section Nephrology & Urology)
Integrated Ozone Therapy and Physical Rehabilitation for Musculoskeletal Disorders: A Comprehensive Approach submission deadline 20 Aug 2026 | Viewed by 7 | Submission Open
Keywords: ozone therapy; physical rehabilitation; musculoskeletal disorders; integrative medicine; rehabilitation therapy; regenerative medicine; clinical outcomes
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Outcomes of Glaucoma Surgery: Visual Acuity, Effectiveness and Quality of Life submission deadline 21 Aug 2026 | Viewed by 43 | Submission Open
Keywords: glaucoma surgery; visual acuity; intraocular pressure; surgical outcomes; trabeculectomy; microinvasive glaucoma surgery; postoperative complications; functional vision
(This special issue belongs to the Section Ophthalmology)
Advancements in Cardiomyopathies: Diagnosis, Treatment and Management—2nd Edition submission deadline 24 Aug 2026 | Viewed by 42 | Submission Open
Keywords: cardiomyopathies; multimodality imaging; cardiac magnetic resonance; genetic testing; cardiogenetics; genetic cardiovascular disease; rare cardiovascular diseases; risk stratification; genotype– phenotype correlations; rare variant interpretation; arrhythmias
(This special issue belongs to the Section Cardiology)
Current and Emerging Strategies in Ischemic Stroke: Diagnosis, Treatment, and Prevention submission deadline 25 Aug 2026 | Viewed by 62 | Submission Open
Keywords: diagnosis; digital medicine; epidemiology; ischemic stroke; machine learning; neurorehabilitation; prevention; stroke imaging; treatment
(This special issue belongs to the Section Clinical Neurology)
Knee Arthroplasty: Recent Advances and Future Challenges
edited by Matteo Marullo
submission deadline 25 Aug 2026 | Viewed by 58 | Submission Open
Keywords: knee arthroplasty; implant design; robotic surgery; revision surgery; biomechanics; clinical outcomes; perioperative care; fast-track surgery; digital orthopedics; partial knee replacement
(This special issue belongs to the Section Orthopedics)
Kidney Transplantation: From Donor Selection to Recipient Outcomes
edited by Basma Merhi and Reginald Gohh
submission deadline 25 Aug 2026 | Viewed by 40 | Submission Open
Keywords: kidney transplantation; end-stage renal disease (ESRD); living-donor kidney transplantation; deceased-donor kidney transplantation; organ shortage; dialysis waiting time; transplant candidate evaluation; immunosuppression
(This special issue belongs to the Section Nephrology & Urology)
Advances in Percutaneous Coronary Intervention: Techniques, Tools and Outcomes
edited by Takashi Ashikaga
submission deadline 25 Aug 2026 | Viewed by 35 | Submission Open
Keywords: percutaneous coronary intervention; orbital atherectomy; coronary artery calcification; intravascular ultrasound (IVUS); optical coherence tomography (OCT)
(This special issue belongs to the Section Cardiovascular Medicine)
Motor Activity and Cognitive Development in Early Childhood: Clinical Implications submission deadline 25 Aug 2026 | Viewed by 33 | Submission Open
Keywords: motor activity; cognitive development; early childhood; neurodevelopmental disorders; autism spectrum disorder; attention-deficit/hyperactivity disorder; developmental coordination disorder; preterm birth
(This special issue belongs to the Section Clinical Neurology)
Hand Surgery in Practice: Current Evidence and Emerging Techniques
edited by Guy Rubin
submission deadline 25 Aug 2026 | Viewed by 33 | Submission Open
Keywords: trauma; mallet; burn; nerve; tendon
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Hypertension in Adults: Current Updates on Diagnosis, Treatment and Management—Second Edition
edited by Emelina Stambolliu and Antonios A. Argyris
submission deadline 25 Aug 2026 | Viewed by 30 | Submission Open
Keywords: essential hypertension; nighttime blood pressure; blood pressure measurement; blood pressure management; blood pressure medical treatment; hypertension thresholds
(This special issue belongs to the Section Vascular Medicine)
Gastrointestinal Cancer: Outcomes and Therapeutic Management—2nd Edition
edited by Maximos Frountzas
submission deadline 25 Aug 2026 | Viewed by 29 | Submission Open
Keywords: surgical oncology; gastrointestinal cancer; esophageal; gastric; hepatic; biliary; pancreatic; colon; rectal; neoplasm
(This special issue belongs to the Section Oncology)
Complications of Laparoscopic Cholecystectomy: Surgical Outcomes and Clinical Challenges
edited by
submission deadline 25 Aug 2026 | Viewed by 22 | Submission Open
Keywords: laparoscopic cholecystectomy; bile duct injury; management of intraoperative injuries; surgical outcomes; postoperative infections
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Bariatric Surgery: Clinical Advances and Future Directions submission deadline 25 Aug 2026 | Viewed by 21 | Submission Open
Keywords: metabolic surgery; bariatric surgery; reflux; laparoscopy; conversion surgery; obesity
(This special issue belongs to the Section General Surgery)
Etiology, Diagnosis, and Management of Upper Gastrointestinal Disorders: 2nd Edition
edited by
submission deadline 25 Aug 2026 | Viewed by 21 | Submission Open
Keywords: esophagus; stomach; duodenum; DGBI; FGIDs; helicobacter; eosinophilic esophagitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Updates of Pediatric Craniofacial Surgery
edited by Federica Tosi
submission deadline 25 Aug 2026 | Viewed by 19 | Submission Open
Keywords: pediatric craniofacial surgery; craniosynostosis; near-infrared spectroscopy; blood transfusion; perioperative monitoring; pediatric anesthesia; hemodynamic management; tissue oxygenation
(This special issue belongs to the Section Clinical Pediatrics)
Personalized Therapy and Clinical Outcome for Vasculitis
edited by
submission deadline 25 Aug 2026 | Viewed by 19 | Submission Open
Keywords: immune-mediated systemic vasculitis; personalized therapy; treatment; outcome; biomarkers; risk factors; management; multidisciplinary care
(This special issue belongs to the Section Immunology & Rheumatology)
Emerging Trends and Therapeutic Innovations in Corneal and Ocular Surface Disorders
edited by and Špela Štunf Pukl
submission deadline 25 Aug 2026 | Viewed by 6 | Submission Open
Keywords: corneal diseases; ocular surface disorders; regenerative medicine; stem cell therapy; gene therapy; nanomedicine and targeted drug delivery
(This special issue belongs to the Section Ophthalmology)
Recent Advances and Future Perspective of Subarachnoid Hemorrhage
edited by
submission deadline 26 Aug 2026 | Viewed by 10 | Submission Open
Keywords: subarachnoid bleeding; neuromonitoring; neuroimaging; delayed cerebral infarction; biomarkers; personalized medicine; AI-guided decision support; outcome
(This special issue belongs to the Section Clinical Neurology)
Clinical Updates in Heart Failure: Innovations in Diagnosis, Therapy and Management
edited by Paolo Severino
submission deadline 28 Aug 2026 | Viewed by 38 | Submission Open
Keywords: heart failure; HFrEF therapy; HFpEF phenotyping; right ventricular dysfunction; renal congestion assessment; diuretic resistance; NT-proBNP dynamics; cardiac imaging; post-discharge management
(This special issue belongs to the Section Cardiology)
Chronic Obstructive Pulmonary Disease (COPD): Treatment and Management—Second Edition
edited by and Alfredo Antonio Chetta
submission deadline 31 Aug 2026 | Viewed by 37 | Submission Open
Keywords: chronic obstructive pulmonary disease (COPD); treatable traits; precision medicine; COPD comorbidities; COPD mortality
(This special issue belongs to the Section Respiratory Medicine)
The New Perspective in Transcatheter Aortic Valve Implantation (TAVI)
edited by Salvatore Giordano, Arturo Giordano and Nicola Corcione
submission deadline 31 Aug 2026 | Viewed by 36 | Submission Open
Keywords: transcatheter aortic valve implantation (TAVI); structural heart intervention; aortic stenosis; valve technology and durability; imaging and procedural optimization
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Management of Type 1 Diabetes: 2nd Edition
edited by Carmen Quirós
submission deadline 31 Aug 2026 | Viewed by 28 | Submission Open
Keywords: type 1 diabetes; continuous glucose monitoring; hybrid closed loop; hypoglycemia; physical activity; new onset type 1 diabetes; pre-stage 3 type 1 diabetes; smart insulin pens
(This special issue belongs to the Section Endocrinology & Metabolism)
Advances in Anticoagulant and Antiplatelet Therapy for Coronary Artery Disease: 2nd Edition
edited by
submission deadline 31 Aug 2026 | Viewed by 20 | Submission Open
Keywords: platelet; anticoagulant therapy; antiplatelet therapy; coronary artery disease (CAD); atrial fibrillation (AF); thromboembolic events; myocardial ischemic; bleeding events; aspirin; clopidogrel; cardiovascular and cerebrovascular diseases; diagnosis and treatment; percutaneous coronary intervention; acute coronary syndrome
(This special issue belongs to the Section Cardiology)
Optimizing the Surgical Journey: From Abdominal Operation to Recovery
edited by and Carlo Bergamini
submission deadline 1 Sep 2026 | Viewed by 43 | Submission Open
Keywords: surgical complications; comanagement; comorbidities; elective surgical procedure; emergency surgery procedure; multidisciplinary approach; hospitalist
(This special issue belongs to the Section General Surgery)
Cardiac Intensive Care Units: Clinical Advances and Future Challenges
edited by Luca Baldetti
submission deadline 10 Sep 2026 | Viewed by 11 | Submission Open
Keywords: cardiac intensive care; heart failure; cardiogenic shock; mechanical circulatory support; invasive hemodynamic monitoring; acute cardiac care; shock; myocardial infarction
(This special issue belongs to the Section Cardiology)
Current Challenges in Clinical Dentistry: 3rd Edition
edited by and
submission deadline 15 Sep 2026 | Viewed by 71 | Submission Open
Keywords: artificial intelligence; clinical dentistry; cutting-edge device and technology; dental material; challenging hypothesis; preventive dentistry; sleep medicine; digital dentistry; smart dentistry; stomatognathic function
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
State-of-the-Art of Lung Surgery: Modern Horizons in Lung Cancer Treatment
edited by and Edouard Sage
submission deadline 15 Sep 2026 | Viewed by 17 | Submission Open
Keywords: lung-cancer-surgery; thoracic oncology; RATS; VATS; induction therapy; neoadjuvant-immunotherapy; non-intubated thoracic surgery; NITS; segmentectomy; lung-sparing surgery; 3D-reconstruction
(This special issue belongs to the Section General Surgery)
Treatment and Clinical Management of Necrotizing Pancreatitis submission deadline 20 Sep 2026 | Viewed by 60 | Submission Open
Keywords: necrotizing pancreatitis; infected necrosis; step-up approach; necrosectomy; minimally invasive surgery; artificial intelligence; lumen-apposing metal stent; pancreatic necrosis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
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