Circadian Genes and Lifestyle–Related Cancer
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Oncology".
Deadline for manuscript submissions: closed (31 March 2021) | Viewed by 163
Special Issue Editor
Special Issue Information
Dear Colleagues,
The circadian (~24 h) rhythm is driven by central and peripheral clocks. These stable clock mechanisms are primarily maintained through positive and negative feedback loops comprising various circadian genes (core clock genes including CLOCK, NPAS2, ARNTL, CSNKIE, CRY1, CRY2, PER1, PER2, and PER3). Moreover, it is estimated that the expression of about 5%–10% of all genes is controlled by circadian genes. Regarding the link between circadian rhythm disruption and cancer, it has been hypothesized that the clock genes related to circadian rhythm have an influence on cell proliferation and apoptosis, and a disruption in the circadian rhythm affects these genes, with a knock-on effect on carcinogenesis. Given the possible links between circadian genes disruption and lifestyle-related cancer, there is a need to investigate lifestyle factors associated with an increased risk of cancer incidence.
For an upcoming Special Issue in the Journal of Clinical Medicine, we invite investigators to contribute manuscripts such as perspectives, reviews, and original research papers on potential and related topics:
- Association between circadian genes and lifestyle in cancer;
- Expression levels of circadian genes;
- Single‐nucleotide polymorphism of circadian genes;
- Methylation levels in circadian genes;
- Diet and dietary behaviors (e.g., poor diet, high-fat and meat diets, diet‐dependent acid load, dietary acrylamide);
- Role of lifestyle factors (e.g., sleep, stress, physical inactivity, and smoking) on circadian gene levels.
As Guest Editor of this Special Issue, I am excited to meet scientists interested in this topic and I hope for many interesting articles on this issue. With your help, we will create a complete Issue that will allow readers to summarize the current state of knowledge on "Circadian Genes and Lifestyle-Related Cancer", and will give new opportunities to improve the prevention and treatment of cancer.
Dr. Edyta Wieczorek
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- circadian disruption
- circadian genes
- cancer
- DNA methylation
- gene expression
- SNP
- lifestyle
- diet
- sleep
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
