Head and Neck Cancer: Clinical Diagnostics and Treatments
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Otolaryngology".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 4
Special Issue Editor
Special Issue Information
Dear Colleagues,
Head and neck cancer is a collective term that includes several types of cancers—with different diagnostic and treatment modalities—categorized by the area in which they originate. Depending on its site, the cancer interferes with e.g., chewing/swallowing (oral cavity, pharynx), voice (larynx), breathing (sinuses and nose cavity), salivation (salivary glands), etc. Thus, both the cancer itself and treatments interfere with function and sometimes cosmetics.
Globally it is estimated that approximately 900,000 new cases of head and neck cancer occur annually (2018). The most common type is the squamous cell carcinoma. The overall 5-year survival rate of all patients with head and neck cancer is approximately 60 percent but with considerable variations in survival depending on the primary site of the cancer. The most important parameter for survival is early detection.
For almost two centuries surgery was the only treatment option. In today’s multidisciplinary treatment, often aiming at organ preservation, surgery is frequently combined with not only radiotherapy but also with cytotoxic drugs, targeted drugs, and immunotherapy. Improved diagnostics (e.g., MRI, PET, sentinel node technique) have refined both the delineation of the cancer itself and the detection of eventual spread to regional lymph nodes or extra-regional metastases. To be noted is that even a new disease has emerged in the past 20-25 years—HPV-associated cancers of the tongue base and the tonsils.
To further increase survival rates, both surgical and drug-induced therapies must be improved through international clinical and basic science cooperation. The aim of this Special Issue is to gather new knowledge to improve treatment of head and neck patients.
Prof. Dr. Matti Anniko
Guest Editor
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Keywords
- head and neck cancer
- treatment
- surgery
- chemotherapy
- immunotherapy
- diagnostics
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