Emerging Trends in Chemical Ecology: Towards Sustainable and Scalable Pest Management Solutions

A special issue of Insects (ISSN 2075-4450). This special issue belongs to the section "Insect Pest and Vector Management".

Deadline for manuscript submissions: 30 November 2026 | Viewed by 1421

Editor


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Guest Editor
Chemical Ecology and Natural Products Laboratory, Institute of Biosciences and Applications, National Centre of Scientific Research “Demokritos”, Athens, Greece
Interests: natural products; chemical ecology; semiochemicals; microbial toxins; IPM; insect attractants; pheromones; kairomones; natural metabolites formulation; slow release sytems
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Special Issue Information

Dear Colleagues,

Chemical ecology is undergoing a significant transformation—from fundamental research to the development of practical, scalable, and sustainable pest management strategies. This evolving field is increasingly recognized for its crucial role in reducing chemical pesticide use, enhancing biodiversity, and supporting the transition to organic and climate-smart agriculture. Environmentally friendly and low-carbon-footprint methods are gaining prominence given that they align with key European Commission policy frameworks, such as the Green Deal’s Farm to Fork Strategy and the EU Biodiversity Strategy, which promote food system sustainability and the protection of ecosystems.

The integration of innovative biotechnologies and precision agriculture practices offers sustainable, efficient, and cost-effective solutions for pest control without the accumulation of persistent organic pollutants (POPs). These developments support eco-friendly agricultural practices that respect biodiversity and minimize environmental impact.

This Special Issue will highlight research on emerging trends in chemical ecology, with topics of interest including, but not limited to, the following:

  • Semiochemical production and formulation;
  • Field deployment techniques and technologies;
  • Precision agriculture and targeted application systems;
  • Natural metabolites from plants, insects, and microorganisms;
  • Integration of semiochemicals into Integrated Pest Management (IPM) frameworks;
  • Induced plant resistance against herbivores;
  • Insect behavioral and physiological adaptations to climate change.

We welcome contributions that provide new insights, report novel developments, and offer fresh perspectives that bridge basic science and applied pest management.

Dr. Maria Konstantopoulou
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Insects is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • semiochemicals
  • precision agriculture
  • IPM
  • field application systems
  • formulation

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Published Papers (2 papers)

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Research

15 pages, 3438 KB  
Article
Leaf Age-Dependent Volatile Cues Influence Host Location and Oviposition Preference of Obolodiplosis robiniae on Robinia pseudoacacia
by Weihan Xu, Jiaqiang Zhao, Qike Wang, Zhashenjiacan Bao, Yuan Xu, Haiwei Wu and Juan Shi
Insects 2026, 17(6), 640; https://doi.org/10.3390/insects17060640 - 17 Jun 2026
Viewed by 126
Abstract
Obolodiplosis robiniae (Haldeman) is a specialist herbivore of Robinia pseudoacacia L., and its infestation is closely associated with tender leaf tissues. The ability of gravid females to recognize suitable host tissues is essential for successful oviposition and subsequent population development. Here, we assessed [...] Read more.
Obolodiplosis robiniae (Haldeman) is a specialist herbivore of Robinia pseudoacacia L., and its infestation is closely associated with tender leaf tissues. The ability of gravid females to recognize suitable host tissues is essential for successful oviposition and subsequent population development. Here, we assessed whether leaf age affects the host-selection behavior of O. robiniae and whether volatile organic compounds are associated with this process. Laboratory oviposition assays were used to compare egg deposition on tender leaves and mature leaves of R. pseudoacacia, and Y-tube olfactometer bioassays were performed to evaluate female responses to odors from the two leaf ages. Volatiles released from healthy tender leaves and mature leaves were collected using dynamic headspace sampling and characterized by thermal desorption–gas chromatography–mass spectrometry. Principal component analysis, orthogonal partial least squares discriminant analysis, and variable importance in projection scores were used to compare volatile profiles between leaf ages. Gravid females deposited significantly more eggs on tender leaves than on mature leaves in both choice and no-choice assays. Females also showed a significant olfactory preference for tender-leaf odors when directly offered a choice between volatiles from tender leaves and mature leaves, with 76.47% of responding individuals selecting tender-leaf odors and 23.53% selecting mature-leaf odors. Chemical profiling identified 28 volatile compounds across the two leaf ages, and their composition and relative abundance differed markedly. Among shared compounds, (Z)-3-hexen-1-ol and α-farnesene differed significantly between tender leaves and mature leaves. Multivariate analyses further identified several candidate compounds contributing to leaf age-related volatile differences. These results indicate that leaf age influences both oviposition behavior and odor-mediated host location in O. robiniae. Leaf age-dependent volatile blends may serve as important chemical cues associated with host selection by gravid females and provide a basis for future studies on volatile-mediated management strategies. Full article
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14 pages, 2739 KB  
Article
From Factory to Field: Sex Pheromone of Plutella xylostella Produced in Yeast Cell-Factories Validated in Laboratory and Field Trials
by Petri-Christina Betsi, Eleni Koutsoumpeli, Irina Borodina, Dimitris Raptopoulos and Maria Konstantopoulou
Insects 2026, 17(3), 303; https://doi.org/10.3390/insects17030303 - 11 Mar 2026
Cited by 1 | Viewed by 782
Abstract
Plutella xylostella (L.) (Lepidoptera: Plutellidae), the diamondback moth (DBM), is a cosmopolitan pest of brassicas. To validate and compare the performance of yeast-derived sex pheromone components with chemically synthesized ones, we studied the behavioral and electrophysiological responses (EAGs) of male DBM adults. In [...] Read more.
Plutella xylostella (L.) (Lepidoptera: Plutellidae), the diamondback moth (DBM), is a cosmopolitan pest of brassicas. To validate and compare the performance of yeast-derived sex pheromone components with chemically synthesized ones, we studied the behavioral and electrophysiological responses (EAGs) of male DBM adults. In addition, using gas chromatography coupled with electroantennographic detection (GC-EAD), we examined whether any residual impurities present in yeast-derived pheromone components can be perceived by the insects’ antennae and are thus capable of interfering with normal behavior. Furthermore, we assessed the performance of the yeast-derived pheromones under field conditions through monitoring trials conducted in cabbage crops in Greece. Electrophysiological and behavioral assays revealed equivalent responses from the insects to both the yeast-derived (BIO) and chemically synthesized (CHEM) pheromone blends. Consistent with this, GC-EAD results showed no significant differences in antennal response to minor impurities present in the BIO blend compared to the CHEM blend. Finally, it was demonstrated that the binary pheromone blend—comprising (Z)-11-hexadecenal and (Z)-11-hexadecenyl acetate derived from (Z)-11-hexadecen-1-ol produced by yeast cell-factories—was as efficient and specific for trapping male moths in cabbage fields as the conventional ternary synthetic blend [(Z)-11-hexadecenal and (Z)-11-hexadecenyl acetate and (Z)-11-hexadecen-1-ol]. The yeast-derived mixture contained small amounts of unoxidized (Z)-11-hexadecen-1-ol due to incomplete oxidation. Full article
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