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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms of Cardiac Development and Disease (Second Edition) submission deadline 29 Apr 2026 | Viewed by 31 | Submission Open
Keywords: cardiac development; cardiac repair; regeneration; cardiac cell-cell interaction; fibrosis; remodeling; molecular mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights and Therapeutic Innovations in Neuromuscular Diseases submission deadline 30 Apr 2026 | Viewed by 20 | Submission Open
Keywords: neuromuscular disorders; molecular mechanisms; gene therapies; RNA therapies; small molecules
(This special issue belongs to the Section Molecular Neurobiology)
Molecular and Signaling Pathways in Pathological Changes of Esophageal, Gastric and Intestinal Epithelial Cells and Methods of Cell Protective Treatment
edited by
submission deadline 30 Apr 2026 | Viewed by 20 | Submission Open
Keywords: gastrointestinal epithelial cells; cellular signaling; molecular pathways; cell damage; cell protection; esophageal integrity; gastric secretion; gastric ulcer; duodenal ulcer; intestinal digestion and absorption; intestinal integrity; inflammatory bowel disease; irritable bowel syndrome; ulcerative colitis; Crohn’ s disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Gene Therapy for Ocular Diseases: Mechanisms, Advances and Therapeutic Applications
edited by Jiang-Hui Wang
submission deadline 30 Apr 2026 | Viewed by 10 | Submission Open
Keywords: AAV; capsid engineering; gene therapy; retinal diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Computer Simulation Insight Into Ligand-Receptor Interaction submission deadline 30 Apr 2026 | Viewed by 4 | Submission Open
Keywords: structure– activity relationship (SAR); free energy perturbation (FEP); structure-based drug design (SBDD); machine learning in drug discovery; hybrid qm/mm methods; binding affinity prediction; enhanced sampling techniques; target binding kinetics
(This special issue belongs to the Section Molecular Informatics)
Natural Compounds in Cancer Therapy and Prevention, 2nd Edition submission deadline 20 May 2026 | 6 articles | Viewed by 19185 | Submission Open
Keywords: cancer therapy cancer prevention; natural compounds; metastasis; immunomodulation; adjuvant therapy; preventive therapy; drug discovery; natural drugs
(This special issue belongs to the Section Molecular Pharmacology)
Fascial Anatomy and Histology: Advances in Molecular Biology
edited by
submission deadline 20 May 2026 | 4 articles | Viewed by 15396 | Submission Open
Keywords: fascia; connective tissue; myofascial pain; collagen; hyaluronan
(This special issue belongs to the Section Molecular Biology)
Pathogenesis and Novel Therapeutic Approaches for Sarcomas
edited by Francisco Giner
submission deadline 20 May 2026 | 4 articles | Viewed by 8237 | Submission Open
Keywords: soft tissue tumors; bone tumors; molecular biology; target therapies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cell Organelle Stress Responses and Implications in Human Diseases
edited by
submission deadline 20 May 2026 | 2 articles | Viewed by 1553 | Submission Open
Keywords: organelle stresses; mitochondria; ER; lysosome; human diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Pancreatic Diseases: Molecular Pathology and Therapeutics
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 839 | Submission Open
Keywords: pancreatic cancer; acute pancreatitis; chronic pancreatitis; diabetes; inflammation; molecular markers; therapeutic strategies; genetic predispositions; diagnostic tools
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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