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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms Underlying the Pathogenesis of Genetic Diseases
edited by
submission deadline 10 Sep 2026 | 7 articles | Viewed by 11796 | Submission Open
Keywords: genetic diseases; genotype–phenotype correlations; multi-omics approaches; current and investigational therapeutical approaches; personalized medicine
(This special issue belongs to the Section Molecular Genetics and Genomics)
Cellular and Molecular Progression of Cardiovascular Diseases: 2nd Edition submission deadline 10 Sep 2026 | 5 articles | Viewed by 4473 | Submission Open
Keywords: cardiovascular diseases; multi-omics data; biomarkers; molecular level
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Exercise in Health and Diseases: From the Molecular Perspectives
edited by and Danielle Dias
submission deadline 10 Sep 2026 | 4 articles | Viewed by 3693 | Submission Open
Keywords: exercise physiology; molecular mechanisms of exercise; exercise-induced cellular signaling; metabolic signaling pathways; redox biology and exercise
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Properties and Applications of Nanoparticles and Nanomaterials: 4th Edition
edited by Xiaogang Li
submission deadline 10 Sep 2026 | 1 articles | Viewed by 1079 | Submission Open
Keywords: nanostructures; nanoparticles; microstructure characterization; material design; evaluation of mechanical properties; applications of nanomaterials
(This special issue belongs to the Section Molecular Nanoscience)
Nanomaterials for Targeted Therapy and Drug Delivery
edited by Ceren Kimna
submission deadline 10 Sep 2026 | Viewed by 366 | Submission Open
Keywords: nanocarriers ; targeted therapies ; translational nanomedicine ; nano-bio interactions
(This special issue belongs to the Section Molecular Nanoscience)
Pain: From Bench to Bedside
edited by and Robert J. Yong
submission deadline 20 Sep 2026 | 1 articles | Viewed by 56152 | Submission Open
Keywords: CGRP pathway; chronic pain; drug discovery; ion channels; machine learning; molecular targets; neuroimmune signaling; non-opioid analgesics; translational pain research; Afrikaans; Albanian; Amharic; Arabic; Armenian; Azerbaijani; Bengali; Bulgarian; Catalan; Croatian; Czech; Danish; Dutch; English; Estonian; Finnish; French; German; Greek; Gujarati; Haitian Creole; Hebrew; Hindi; Hungarian; Icelandic; Indonesian; Italian; Japanese; Kannada; Kazakh; Khmer; Korean; Kurdish (Kurmanji); Lao; Latvian; Lithuanian; Malagasy; Malay; Malayalam; Maltese; Maori; Marathi; Myanmar (Burmese); Nepali; Norwegian; Pashto; Persian; Polish; Portuguese; Punjabi; Romanian; Russian; Samoan; Simplified Chinese; Slovak; Slovenian; Spanish; Swedish; Tamil; Telugu; Thai; Traditional Chinese; Turkish; Ukrainian; Urdu; Vietnamese; Welsh
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Autoimmune Diseases: From Pathogenesis to Treatment and Prognostic Markers
edited by Alessandra Bettiol
submission deadline 20 Sep 2026 | 13 articles | Viewed by 44449 | Submission Open
Keywords: autoimmune diseases; inflammation; immunity; pathogenesis; immunosuppressants; biologics; biomarkers
(This special issue belongs to the Section Molecular Immunology)
Drug Delivery to the Central Nervous System: From Design, Synthesis, and Evaluation
edited by
submission deadline 20 Sep 2026 | 6 articles | Viewed by 40512 | Submission Open
Keywords: central nervous system; central nervous system diseases; drug delivery systems; blood–brain barrier; blood–cerebrospinal fluid barrier; drug design; nanomedicine; neuropharmacology; neuroprotective agents; biomarkers
(This special issue belongs to the Section Molecular Neurobiology)
Plant Metabolomics: Uncovering the Hidden World of Plant Secondary Metabolites
edited by
submission deadline 20 Sep 2026 | 14 articles | Viewed by 33449 | Submission Open
Keywords: metabolomics; secondary metabolites; plant biochemistry; mass spectrometry; NMR spectroscopy; plant signaling pathways; natural products; chemical ecology; metabolic profiling; phytochemicals; medicinal plants; herbal medicines
(This special issue belongs to the Section Molecular Plant Sciences)
New Insights in Antibody Therapy
edited by
submission deadline 20 Sep 2026 | 4 articles | Viewed by 20353 | Submission Open
Keywords: biological therapy; antibody therapy; non-communicable diseases; infectious diseases; chronic disease
(This special issue belongs to the Section Molecular Immunology)
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