Molecular Research on Actinomycetes-Derived Natural Products
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 20 June 2026 | Viewed by 788
Special Issue Editor
Special Issue Information
Dear Colleagues,
Natural products (NPs) comprise a wide variety of molecules that are vital sources of bioactive compounds, with established applications in therapeutics, food, and agriculture. Approximately 50% of non-biological drugs originate from natural products, including those derived from them or their mimics. Actinomycetes, a group of Gram-positive filamentous bacteria primarily represented by Streptomyces, have been particularly significant in the discovery of these natural products.
Unfortunately, the traditional methods for bioactivity-guided screening of bioactive NPs have yielded only a limited amount of progress since the conclusion of the golden age of exploration in the last century. However, the rise of omics science and new computational advancements have revitalized NP research, ushering in a promising era of discovery.
This Special Issue aims to address diverse intersections of actinomycetes and natural products, including, but not limited to, advances in discovery, engineering, and characterization.
Dr. Fong Tian Wong
Guest Editor
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Keywords
- actinomycetes
- natural products
- actinobacterial
- genome mining
- omics
- secondary metabolites
- genetic engineering
- discovery
- structural diversity
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