New Insights into the Mechanisms of Neurodegeneration and Regeneration: From Bench to Bedside
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 730
Special Issue Editor
Interests: neuronal network; neuron; neuroplasticity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue aims to shed greater light on the mechanisms of the degeneration and regeneration of nervous system components across the multidisciplinary field of neuroscience. Both processes, neurodegeneration and regeneration, involve complex and interconnected pathways, associated with changes in the internal microenvironment and cellular metabolism. Neurodegeneration is multifaceted, encompassing protein misfolding and aggregation, oxidative stress, mitochondrial dysfunction, neuroinflammation, and disorders of calcium homeostasis. On the contrary, nervous system regeneration implicates events observed during embryonal development: axonal regrowth, neurogenesis, and synaptogenesis, and alterations in synaptic plasticity. Contributions highlighting these aspects of the nervous system under normal and pathological conditions, as well as variations in brain development, are welcome. We encourage neuroscientists from many subfields to share their ideas, reviews, and original studies, with the hope that this Issue will provide a platform for debate on the etiology of neurodegenerative diseases, thus giving impetus to further identify and validate new therapeutic approaches to the plethora of neuropathological entities.
Dr. Irina Ivanova Stoyanova
Guest Editor
Manuscript Submission Information
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Keywords
- neurodegeneration
- neuroregeneration
- molecular neurobiology
- brain development
- developmental brain disorders
- synaptogenesis
- synaptic plasticity
- cognitive neuroscience
- neurotrauma
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