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Plasma-Based Technologies for Food Safety and Health Enhancement

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 30 January 2026 | Viewed by 1860

Special Issue Editor


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Guest Editor
Plasma Bioscience Research Center, Applied Plasma Medicine Center, Kwangwoon University, Seoul, Republic of Korea
Interests: atmospheric pressure plasma; plasma-treated liquid; p53; MAPK pathway; oriental medicine; in silico drug screening
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Special Issue Information

Dear Colleagues,

Cold plasma technology has emerged as a powerful non-thermal approach in food science, offering new possibilities for microbial decontamination, shelf-life extension, and the promotion of health benefits in food products. This Special Issue aims to explore the molecular mechanisms and biological outcomes of plasma-based technologies in improving food safety and promoting health. Submissions are encouraged on the characterization of reactive species generated by plasma, their interactions with food components, and their effects on microbial pathogens, oxidative stability, and nutrient preservation at the molecular level. Studies involving gene expression, metabolic profiling, or biochemical assays to understand plasma-induced changes are particularly welcome. Reviews and original research on molecular safety evaluation and risk-related biomarkers in plasma-treated food products are also encouraged.

Prof. Dr. Ihn Han
Guest Editor

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Keywords

  • plasma-based technologies
  • food safety
  • microbial pathogens
  • oxidative stability
  • nutrient preservation

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Published Papers (1 paper)

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Research

18 pages, 3095 KB  
Article
Investigating Seed Germination, Seedling Growth, and Enzymatic Activity in Onion (Allium cepa) Under the Influence of Plasma-Treated Water
by Sabnaj Khanam, Young June Hong, Eun Ha Choi and Ihn Han
Int. J. Mol. Sci. 2025, 26(15), 7256; https://doi.org/10.3390/ijms26157256 - 27 Jul 2025
Viewed by 1581
Abstract
Seed germination and early seedling growth are pivotal stages that define crop establishment and yield potential. Conventional agrochemicals used to improve these processes often raise environmental concerns, highlighting the need for sustainable alternatives. In this study, we demonstrated that water treated with cylindrical [...] Read more.
Seed germination and early seedling growth are pivotal stages that define crop establishment and yield potential. Conventional agrochemicals used to improve these processes often raise environmental concerns, highlighting the need for sustainable alternatives. In this study, we demonstrated that water treated with cylindrical dielectric barrier discharge (c-DBD) plasma, enriched with nitric oxide (NO) and reactive nitrogen species (RNS), markedly enhanced onion (Allium cepa) seed germination and seedling vigor. The plasma-treated water (PTW) promoted rapid imbibition, broke dormancy, and accelerated germination rates beyond 98%. Seedlings irrigated with PTW exhibited significantly increased biomass, root and shoot length, chlorophyll content, and antioxidant enzyme activities, accompanied by reduced lipid peroxidation. Transcriptomic profiling revealed that PTW orchestrated a multifaceted regulatory network by upregulating gibberellin biosynthesis genes (GA3OX1/2), suppressing abscisic acid signaling components (ABI5), and activating phenylpropanoid metabolic pathways (PAL, 4CL) and antioxidant defense genes (RBOH1, SOD). These molecular changes coincided with elevated NO2 and NO3 levels and finely tuned hydrogen peroxide dynamics, underpinning redox signaling crucial for seed activation and stress resilience. Our findings establish plasma-generated NO-enriched water as an innovative, eco-friendly technology that leverages redox and hormone crosstalk to stimulate germination and early growth, offering promising applications in sustainable agriculture. Full article
(This article belongs to the Special Issue Plasma-Based Technologies for Food Safety and Health Enhancement)
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