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Inorganic Nanostructures in Biological Systems

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioinorganic Chemistry".

Deadline for manuscript submissions: closed (27 May 2016) | Viewed by 110410

Special Issue Editor

Dr. Vladimir Sivakov
E-Mail Website1 Website2
Guest Editor
Leibniz Institute of Photonic Technology, Jena, Germany
Interests: semiconducting nanostructures; functional oxides; cancer theranostics; nanomedicine; drug delivery; (bio)photonic

Special Issue Information

Dear Colleagues,

Biomedicine and biophotonics related businesses are currently growing at a breathtaking pace, thereby comprising one of the fastest growing sectors of innovative economy. This sector is truly interdisciplinary, including, very prominently, the development of novel nanomaterials, light sources, or novel device/equipment concepts to carry out photon conversion or interaction. The great importance of disease diagnosis at a very early stage and of the individual treatment of patients requires a carefully targeted therapy and the ability to induce cell death selectively in diseased cells. Despite the tremendous progress achieved by using quantum dots or organic molecules for bio-imaging and drug delivery, some problems still remain to be solved: (i) reduction of skin/tissue sensitivity in the post treatment period, (ii) increased selectivity for tumor accumulation, and (iii) enhancement of treatment efficiency. Other potential problems include (i) cyto- and genotoxicity, (ii) slow clearance, (iii) accumulation in the organism, and (iv) low chemical stability. Significant expectations are now related to novel classes of inorganic materials, such as silicon-based, metal or metal oxide, upconvertor nanoparticles, etc., which could exhibit more stable and promising characteristics for both medical diagnostics and therapy. For this reason, new labeling and drug delivery agents for medical application is an important field of research with strongly-growing potential.

Dr. Vladimir Sivakov
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Drug delivery
  • Nanoparticles
  • Theranostic
  • Nanomedicine
  • Cancer
  • Tumor
  • Silicon
  • Upconvertor
  • Gold
  • Carbon-based nanoparticles
  • Metal oxide nanoparticles
  • Photoacoustic
  • Raman spectroscopy
  • Confocal Microscopy
  • Toxicity
  • Cell proliferation

Published Papers (15 papers)

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Jump to: Review

3899 KiB  
Linear and Non-Linear Optical Imaging of Cancer Cells with Silicon Nanoparticles
Int. J. Mol. Sci. 2016, 17(9), 1536; https://doi.org/10.3390/ijms17091536 - 12 Sep 2016
3599 KiB  
Trichostatin A Enhances the Apoptotic Potential of Palladium Nanoparticles in Human Cervical Cancer Cells
Int. J. Mol. Sci. 2016, 17(8), 1354; https://doi.org/10.3390/ijms17081354 - 19 Aug 2016
10045 KiB  
Accumulation and Toxicity of Superparamagnetic Iron Oxide Nanoparticles in Cells and Experimental Animals
Int. J. Mol. Sci. 2016, 17(8), 1193; https://doi.org/10.3390/ijms17081193 - 19 Aug 2016
3217 KiB  
Evaluation of Pulmonary Toxicity of Zinc Oxide Nanoparticles Following Inhalation and Intratracheal Instillation
Int. J. Mol. Sci. 2016, 17(8), 1241; https://doi.org/10.3390/ijms17081241 - 01 Aug 2016
2517 KiB  
Liposomes Loaded with Hydrophobic Iron Oxide Nanoparticles: Suitable T2 Contrast Agents for MRI
Int. J. Mol. Sci. 2016, 17(8), 1209; https://doi.org/10.3390/ijms17081209 - 27 Jul 2016
3661 KiB  
Nanodiamonds for Medical Applications: Interaction with Blood in Vitro and in Vivo
Int. J. Mol. Sci. 2016, 17(7), 1111; https://doi.org/10.3390/ijms17071111 - 12 Jul 2016
4784 KiB  
Bacteria-Templated NiO Nanoparticles/Microstructure for an Enzymeless Glucose Sensor
Int. J. Mol. Sci. 2016, 17(7), 1104; https://doi.org/10.3390/ijms17071104 - 11 Jul 2016
11954 KiB  
Dual-Labeled Near-Infrared/99mTc Imaging Probes Using PAMAM-Coated Silica Nanoparticles for the Imaging of HER2-Expressing Cancer Cells
Int. J. Mol. Sci. 2016, 17(7), 1086; https://doi.org/10.3390/ijms17071086 - 07 Jul 2016
1746 KiB  
In Situ Electron Microscopy of Lactomicroselenium Particles in Probiotic Bacteria
Int. J. Mol. Sci. 2016, 17(7), 1047; https://doi.org/10.3390/ijms17071047 - 30 Jun 2016
3399 KiB  
Poly(acrylic acid)-regulated Synthesis of Rod-Like Calcium Carbonate Nanoparticles for Inducing the Osteogenic Differentiation of MC3T3-E1 Cells
Int. J. Mol. Sci. 2016, 17(5), 639; https://doi.org/10.3390/ijms17050639 - 06 May 2016
1049 KiB  
Fluorescence-Lifetime Imaging Microscopy for Visualization of Quantum Dots’ Endocytic Pathway
Int. J. Mol. Sci. 2016, 17(4), 473; https://doi.org/10.3390/ijms17040473 - 30 Mar 2016
6041 KiB  
Biodegradation of Single-Walled Carbon Nanotubes in Macrophages through Respiratory Burst Modulation
Int. J. Mol. Sci. 2016, 17(3), 409; https://doi.org/10.3390/ijms17030409 - 22 Mar 2016


Jump to: Research

4051 KiB  
Silver Nanoparticle-Mediated Cellular Responses in Various Cell Lines: An in Vitro Model
Int. J. Mol. Sci. 2016, 17(10), 1603; https://doi.org/10.3390/ijms17101603 - 22 Sep 2016
7625 KiB  
Towards Effective Photothermal/Photodynamic Treatment Using Plasmonic Gold Nanoparticles
Int. J. Mol. Sci. 2016, 17(8), 1295; https://doi.org/10.3390/ijms17081295 - 09 Aug 2016
1996 KiB  
Usefulness of Intratracheal Instillation Studies for Estimating Nanoparticle-Induced Pulmonary Toxicity
Int. J. Mol. Sci. 2016, 17(2), 165; https://doi.org/10.3390/ijms17020165 - 27 Jan 2016
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