Inorganic Nanostructures in Biological Systems
Deadline for manuscript submissions: closed (27 May 2016) | Viewed by 110410
Biomedicine and biophotonics related businesses are currently growing at a breathtaking pace, thereby comprising one of the fastest growing sectors of innovative economy. This sector is truly interdisciplinary, including, very prominently, the development of novel nanomaterials, light sources, or novel device/equipment concepts to carry out photon conversion or interaction. The great importance of disease diagnosis at a very early stage and of the individual treatment of patients requires a carefully targeted therapy and the ability to induce cell death selectively in diseased cells. Despite the tremendous progress achieved by using quantum dots or organic molecules for bio-imaging and drug delivery, some problems still remain to be solved: (i) reduction of skin/tissue sensitivity in the post treatment period, (ii) increased selectivity for tumor accumulation, and (iii) enhancement of treatment efficiency. Other potential problems include (i) cyto- and genotoxicity, (ii) slow clearance, (iii) accumulation in the organism, and (iv) low chemical stability. Significant expectations are now related to novel classes of inorganic materials, such as silicon-based, metal or metal oxide, upconvertor nanoparticles, etc., which could exhibit more stable and promising characteristics for both medical diagnostics and therapy. For this reason, new labeling and drug delivery agents for medical application is an important field of research with strongly-growing potential.
Dr. Vladimir Sivakov
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- Drug delivery
- Carbon-based nanoparticles
- Metal oxide nanoparticles
- Raman spectroscopy
- Confocal Microscopy
- Cell proliferation