New Insights into Oxidative Stress and Inflammation in the Pathophysiology and Treatment of Respiratory Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 2803
Special Issue Editor
2. Inserm U1179, University of Paris Saclay (UVSQ), 78000 Versailles, France
Interests: respiratory diseases; Nrf2/keap1-Bach1 signaling; macrophage; physiology; lung; immune regulation; monocyte–macrophage; inflammation; innate immunity; cell biology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Recently, the importance of the respiratory system and the need for novel therapeutic strategies for respiratory diseases have been highlighted by SARS-CoV-2. The airways are constantly exposed to various inhaled pollutants and microbes, which induce oxidative stress and inflammation. Oxidative stress, known to increase the risk of developing many acute and chronic respiratory diseases, is defined by an imbalance between the production of reactive oxygen species and the capacity of antioxidants to counteract the deleterious effects of oxidants. Normal healthy lungs protect themselves against these oxidants with cellular and extracellular antioxidant defense mechanisms throughout the epithelial lining fluid and tissues. Recently, novel therapeutic targets have been implicated in the prevention, or treatment, of respiratory disease by modulating oxidative stress and inflammation. This Special Issue focuses on different aspects of oxidative stress and inflammation in the pathophysiology and treatment of respiratory diseases in animal models. IJMS is a journal of molecular science; thus, pure clinical studies will not be applicable. However, clinical submissions with biomolecular experiments are welcomed.
Prof. Dr. Marcel Bonay
Guest Editor
Manuscript Submission Information
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Keywords
- oxidative stress
- inflammation
- lung
- respiratory disease
- molecular biology
- infection
- therapeutic strategies
- antioxidants
- innate immunity
- animal models
