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Special Issue "Designer Biopolymers: Self-Assembling Proteins and Nucleic Acids"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biophysics".

Deadline for manuscript submissions: 31 July 2019

Special Issue Editors

Guest Editor
Prof. Dr. Ayae Sugawara-Narutaki

Department of Materials Chemistry, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan
Website | E-Mail
Guest Editor
Prof. Dr. Yukiko Kamiya

Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan
Website | E-Mail

Special Issue Information

Dear Colleagues,

Nature has evolved sequence-controlled polymers like DNA and proteins over its long history. The recent rapid progress of synthetic chemistry, DNA recombinant technology, and computational science, as well as the elucidation of molecular mechanisms in biological processes drive us to design ingenious polymers that are inspired by naturally occurring polymers but surpass them in specialized functions. The term “designer biopolymers” refers to polymers consisting of biological building units such as nucleotides, amino acids, and monosaccharides in a sequence-controlled manner. They may contain non-canonical nucleotides/amino acids/monosaccharides, or they may be conjugated to synthetic polymers to acquire specific functions in vitro and in vivo.

This Special Issue particularly focuses on the self-assembling aspect of designer biopolymers. Self-assembly is one common feature in biopolymers to realize their dynamic biological activities, and is strictly controlled by the sequence of biopolymers. In a broad sense, the self-assembly of biopolymers includes double-helix formation of DNA, protein folding, and higher-order protein assembly (e.g., viral capsids). Designer biopolymers are now going beyond what nature evolved: researchers have generated DNA origami, protein cages, peptide nanofibers, and gels. The aim of this Special Issue is to assemble the latest interdisciplinary work on self-assembling designer biopolymers to exchange ideas and encourage new lines of research.

Prof. Dr. Ayae Sugawara-Narutaki
Prof. Dr. Yukiko Kamiya
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • de novo protein design
  • Artificial nucleic acid/peptide
  • Self-assembling peptide/protein
  • DNA nanotechnology
  • Nanofiber and gel of nucleic acid/protein/peptide
  • Stimuli-responsive designer biopolymers
  • Tissue engineering scaffold  

Published Papers

This special issue is now open for submission, see below for planned papers.

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Role of the structurally-conserved protein interface residues on the self-assembly of the viral capsid: thermodynamic stability of the Cowpea Chlorotic Mottle Virus

Authors: Armando Díaz-Valle and Mauricio Carrillo-Tripp
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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