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Special Issue "Biofilms and Bacterial Virulence"
Deadline for manuscript submissions: 31 January 2020.
Interests: biofilm infection; biofilm virulence; biofilm prevention; risks of biofilm formation; eradication methods of biofilm; assay system using different substrates; inter-bacterial biofilm regulation system; MRSA
2. Division of Medical Oncology, Hematology, and Infectious Diseases, Department of Medicine, Fukuoka University, Fukuoka, Japan
Interests: clinical infectious diseases; biofilm infection; Klebsiella pneumoniae infection; travel medicine
Interests: antimicrobial resistance; risks of biofilm formation; epidemiology of MRSA; infection control
Biofilm infections are serious problems in clinical settings. Some bacteria, including Staphylococcus and Pseudomonas aeruginosa, have the ability to form biofilms during their life cycle. Biofilms contribute to bacterial survival and virulence. Most biofilm investigators believe that bacterial properties change when they settle on a surface and form biofilms, which includes the acquisition of nonspecific resistance to anti-bacterial compounds. Biofilms enhance drug resistance more than one hundred times compared to bacteria in the planktonic state, as a consequence of the biofilm’s structural rigidity and/or phenotypic alterations by environmental selection, or gene reconstitution within the confines of the biofilms. The precise nature of these changes is still being unraveled. Even if these changes are understood, eradication of biofilms with drugs is not feasible because the high concentrations required may adversely affect us. For such a disparate situation, the only recourse is to go back to the basics. We may have overlooked something important, such as the exact biofilm risk and bacterial virulence, particularly in the body. This can verify the previous approaches of biofilm investigations.
In this Special Issue, we take a fresh look at this subject with the aim of challenging previous methods and concepts of biofilms. We welcome your articles in this exciting biomedical field.
Dr. Shiro Jimi
Dr. Atsushi Togawa
Dr. Motoyasu Miyazaki
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Biofilm-forming bacteria
- Biofilm eradication
- Anti-biofilm compounds
- Biofilm assay system