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Glycoscience in Neurodegenerative Disorders

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 184

Special Issue Editor


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Guest Editor
National Research Council of Italy (CNR), Department Biomedicine - Institute Biochemistry and Cell Biology (IBBC), Naples, Italy
Interests: aging; dementia; Alzheimer; FTD; progranulin; CD33; TREM2; SIGLEC genes; CRISPR-Cas9; iPSCs Parkinson; neuroinflammation; personalized medicine
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Special Issue Information

Dear Colleagues,

Neurodegenerative disorders are a heterogeneous group of disorders, largely age-dependent, affecting the central nervous system and eventually leading to neurodegeneration. The prevalence of these diseases is increasing, partly due to the aging population, with a consequent growing economic burden on healthcare systems. The current treatments are mostly symptomatic, without affecting the underlying cause of disease, and have no or only slight effects on disease progression. Some mechanisms common to several neurodegenerative conditions have been identified, such as the presence of misfolded protein aggregates, the abnormal accumulation of proteins, RNA toxicity, or translational products from repeat expansion within genes. Advancements in synthetic methods, molecular biology, and analytical techniques have evidenced the key roles that carbohydrates and their conjugates (from simple saccharide units to complex glycans) play in biological processes, such as protein folding, infection, cancer, and immune recognition.

IJMS has organized a series of Special Issues to highlight the latest advancements in this area of science in order to be at the forefront of different fields of research. This editorial initiative of particular relevance, led by Dr. Emilia Vitale, is focused on new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in the field of neurodegenerative disorders, neuroplasticity and glycoscience.

The present Special Issue, entitled “Glycoscience in Neurodegenerative Disorders”, aims to present recent research developments to those involved in this field and the wider community. We welcome contributions from papers which focus on topics within this field.

Dr. Emilia Vitale
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neurodegenerative disorders
  • neurogenetics
  • pathogenesis
  • therapy
  • glycoscience

Published Papers

This special issue is now open for submission.
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