Acid–Base Metabolism, Nutrition, Hormones, and Human Health

Dear Colleagues,

Acid–base metabolism plays a pivotal role in numerous body functions and thus in human health. Kidney function and nutrition are important determinants of acid base status.

Over the last decades, researchers from different disciplines have substantially contributed to our understanding of the short- and long-term impact of certain diets and nutritional habits on acid base status, its balance and its buffering systems including hemoglobin and bicarbonate levels in blood and ammonium, phosphate, and organic acid anion excretion in urine.

The effects of diet on acid–base metabolism are at least partly mediated by hormones or are closely related to changes in major endocrine systems, mostly with significant consequences for kidney health.

Against this background the current Special Issue “Acid–Base Metabolism, Nutrition, Hormones, and Human Health” invites authors working in relevant areas to submit original research articles as well as reviews on hormonal interactions between acid–base metabolism, nutrition and kidney function.

We welcome manuscripts that cover experimental work and human studies into all stages of human life, from young childhood to old adulthood. Potential topics include, but are not limited to, the following endocrine foci related to renal nutrition and acid–base metabolism:

• Insulin secretion and resistance;
• Growth hormone-insulin like growth factor axis;
• Adrenal gland activity, glucocorticoids, cortisol and cortisone;
• Renin–angiotensin system, aldosterone secretion, potassium balance;
• Parathyroid hormone, FGF-23-Klotho axis potentially related to kidney stone risk along with circulating and renally excreted phosphate and calcium;
• Adipo-renal axis, leptin;
• Thyroid gland activity, thyroid hormones and TSH.

Prof. Dr. Thomas Remer
Prof. Dr. Lynda A. Frassetto
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• ammoniagenesis
• FGF-23-Klotho axis
• growth hormone–IGF axis
• hormones
• kidney physiology and function
• NAE
• nutrition
• potassium balance
• PRAL
• renin–angiotensin aldosterone system