Molecular Pharmacology and Metabolic Signaling in Health and Disease

Dear Colleagues,

Molecular pharmacology not only defines the impact of the xenobiotics we consume but also explains the actions of the endogenous hormones, peptides, and enzymes that help to maintain health and homeostasis. Similarly, in the foods we eat and the medicines we consume, they all have the ability to turn on metabolic signaling, which aids in proper functioning of the cells in our body. Problems arise when our endogenous levels of hormones, peptides, and enzymes are altered, leading to either overactivation or underactivation of their targets and resulting in disruption to internal harmony. In the same manner, if we overconsume or underconsume components of our diet or consume medications in high doses or chronically, this could lead to alterations in metabolic signaling and become a stepping stone for disease induction. In short, the medicines and foods we consume and their endogenous components have an intertwined effect on maintaining systemic balance. For this Special Issue series, we are seeking works focused on the importance of cellular pharmacology and metabolic signaling to maintain normal health and also on conditions where cellular pharmacology and metabolic signaling are altered. Factors like diseases states, which could alter our endogenous hormones, peptides, and enzymes; chronic use of certain medications; consuming certain dietary components in excess; lifestyle changes, which could alter our regular metabolic needs including fasting; and overeating are all topics of interest.

In this Special Issue, the major focus will be on molecular pharmacology and metabolic signaling, which impact our normal health and also have significance in various disease conditions. Works involving in vitro studies, in vivo studies, and studies with translation or clinical approaches are also welcome. We will be accepting original research, brief reports, and short and comprehensive review article submissions. We encourage you to submit an abstract to check the suitability of your work for this Special issue and will confirm your eligibility as soon as possible.

We look forward to hearing from you.

Dr. Prasanth Puthanveetil
Guest Editor

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• molecular pharmacology
• cellular signaling
• signal transduction
• mechanism of drugs
• altered metabolism in disease states
• systemic metabolism and health
• altered synthesis and secretion of endogenous agents
• lifestyle modifications
• diet and exercise