Sleep Apnoea and Comorbidity: A Molecular Approache, Treatment, and Clinical Implications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 November 2020) | Viewed by 2945
Special Issue Editor
Interests: obstructive sleep apnoea; sleep fragmentation; inflammation; exosome and biomarkers; cardio-metabolic disease; epigenetics; mesenchymal stem cell
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Obstructive sleep apnoea (OSA) is a common symptom of the upper airway, affecting 2–4% of the global adult population. It is characterized by intermittent hypoxia and frequent arousals due to the repetitive collapse of the upper airway during sleep. These physiological properties lead to activation and propagation of oxidative stress, inflammation, and sympathetic hyperactivity. Accumulated evidence has demonstrated that OSA is closely related to various chronic diseases, including hypertension, diabetes mellitus, dyslipidemia, and neurocognitive dysfunction. Recent epidemiological and experimental studies also show a significant causal relationship between OSA and cancer. Due to the lack of experimental models that can mimic OSA, the underlying mechanisms linking OSA and comorbidities have not been clearly elucidated. However, advances in molecular and biological technologies have made it possible to better understand the pathophysiological phenomena of OSA-related diseases. In this Special Issue, we will cover recent outstanding findings regarding treatment strategies, biomarkers, pathophysiological mechanisms of diseases associated with OSA, important clinical and epidemiological results, and big data analysis. This integrated approach is expected to provide readers with a better understanding of OSA from a molecular perspective.
Prof. Jinkwan Kim
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- obstructive sleep apnoea
- intermittent hypoxia
- inflammation
- biomarkers
- treatment
- cardiovascular disease
- epigenetics
